Chao-Feng Zhang1, Qiong Wang, Mian Zhang. 1. Key Laboratory of Modern Chinese Medicines of Ministry of Education/Research Department of Pharmacognosy, China Pharmaceutical University, Nanjing 210038, China. inchaofeng@126.com
Abstract
OBJECTIVE: To study the chemical constituents of Lighularia altaica. METHODS: Various chromatographic techniques were used to isolate and purify the chemical compounds, their structure were elucidated by means of mass, physico-chemical properties and NMR spectral data. RESULTS: Nine compounds were obtained as: lupeol (1), oleanolic acid (2), 3beta, 16beta-dihydroxy-12-oleanen-28-al (3), ergosterol peroxide (4), stigmasta-7-en-ol (5), 11-hydroxy-10,11-dihydro-euparin (6), 5-hydroxybenzofuran-2(3H) -one- (7), except for beta-sitosterol (8) and daucostrol (9). CONCLUSION: Compounds 3 - 7 are isolated for the first time from this genus, the other compounds are obtained from this plant for the first time.
OBJECTIVE: To study the chemical constituents of Lighularia altaica. METHODS: Various chromatographic techniques were used to isolate and purify the chemical compounds, their structure were elucidated by means of mass, physico-chemical properties and NMR spectral data. RESULTS: Nine compounds were obtained as: lupeol (1), oleanolic acid (2), 3beta, 16beta-dihydroxy-12-oleanen-28-al (3), ergosterol peroxide (4), stigmasta-7-en-ol (5), 11-hydroxy-10,11-dihydro-euparin (6), 5-hydroxybenzofuran-2(3H) -one- (7), except for beta-sitosterol (8) and daucostrol (9). CONCLUSION: Compounds 3 - 7 are isolated for the first time from this genus, the other compounds are obtained from this plant for the first time.