Literature DB >> 1964257

Pharmacological and functional characteristics of metabotropic excitatory amino acid receptors.

D Schoepp1, J Bockaert, F Sladeczek.   

Abstract

Until recently the metabotropic excitatory amino acid receptor could only be distinguished from ionotropic receptors by the nature of its second messenger system--phosphoinositide hydrolysis. However, the advent of new pharmacological tools, in particular the selective agonist trans-ACPD, has now allowed this receptor to be distinguished pharmacologically. Darryle Schoepp, Joel Bockaert and Fritz Sladeczek analyse the new data which can be correlated to functional responses and linked with physiological and pathological conditions.

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Year:  1990        PMID： 1964257     DOI： 10.1016/0165-6147(90)90052-a

Source DB:  PubMed          Journal:  Trends Pharmacol Sci        ISSN： 0165-6147            Impact factor:   14.819


  46 in total

1.  Task-dependent role for dorsal striatum metabotropic glutamate receptors in memory.

Authors:  M G Packard; S F Vecchioli; J P Schroeder; A Gasbarri
Journal:  Learn Mem       Date:  2001 Mar-Apr       Impact factor: 2.460

2.  Specific [3H]glutamate binding in the cerebral cortex and hippocampus of rats during development: effect of homocysteine-induced seizures.

Authors:  J Folbergrová; V Lisý; R Haugvicová; F Stastný
Journal:  Neurochem Res       Date:  1997-05       Impact factor: 3.996

3.  Differential responsiveness of metabotropic glutamate receptors coupled to phosphoinositide hydrolysis to agonists in various brain areas of the adult rat.

Authors:  P Lorenzini; G M Bisso; S Fortuna; H Michalek
Journal:  Neurochem Res       Date:  1996-03       Impact factor: 3.996

4.  Characterization of a metabotropic glutamate receptor: direct negative coupling to adenylyl cyclase and involvement of a pertussis toxin-sensitive G protein.

Authors:  L Prezeau; O Manzoni; V Homburger; F Sladeczek; K Curry; J Bockaert
Journal:  Proc Natl Acad Sci U S A       Date:  1992-09-01       Impact factor: 11.205

5.  Alternative splicing generates metabotropic glutamate receptors inducing different patterns of calcium release in Xenopus oocytes.

Authors:  J P Pin; C Waeber; L Prezeau; J Bockaert; S F Heinemann
Journal:  Proc Natl Acad Sci U S A       Date:  1992-11-01       Impact factor: 11.205

Review 6.  Inhibitory glutamate receptor channels.

Authors:  T A Cleland
Journal:  Mol Neurobiol       Date:  1996-10       Impact factor: 5.590

7.  Actions of agonists of metabotropic glutamate receptors on synaptic transmission and transmitter release in the olfactory cortex.

Authors:  G G Collins
Journal:  Br J Pharmacol       Date:  1993-02       Impact factor: 8.739

8.  Ionotropic non-N-methyl-D-aspartate agonists induce retraction of dendritic spinules from retinal horizontal cells.

Authors:  R Weiler; K Schultz
Journal:  Proc Natl Acad Sci U S A       Date:  1993-07-15       Impact factor: 11.205

9.  Pharmacological characterization of glutamate binding sites in cultured cerebellar granule cells and cortical astrocytes.

Authors:  I Holopainen; P Saransaari; S S Oja
Journal:  Neurochem Res       Date:  1994-02       Impact factor: 3.996

10.  Ligand binding profile of the rat metabotropic glutamate receptor mGluR3 expressed in a transfected cell line.

Authors:  D J Laurie; M Danzeisen; H W Boddeke; B Sommer
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1995-05       Impact factor: 3.000
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