Literature DB >> 19641918

Use of platelet-rich plasma for the treatment of refractory jumper's knee.

Giuseppe Filardo1, Elizaveta Kon, Stefano Della Villa, Ferruccio Vincentelli, Pier Maria Fornasari, Maurilio Marcacci.   

Abstract

The aim of this study was to evaluate the efficacy of multiple platelet-rich plasma (PRP) injections on the healing of chronic refractory patellar tendinopathy after previous classical treatments have failed. We treated 15 patients affected by chronic jumper's knee, who had failed previous nonsurgical or surgical treatments, with multiple PRP injections and physiotherapy. We also compared the clinical outcome with a homogeneous group of 16 patients primarily treated exclusively with the physiotherapy approach. Multiple PRP injections were performed on three occasions two weeks apart into the site of patellar tendinopathy. Tegner, EQ VAS and pain level were used for clinical evaluation before, at the end of the treatment and at six months follow-up. Complications, functional recovery and patient satisfaction were also recorded. A statistically significant improvement in all scores was observed at the end of the PRP injections in patients with chronic refractory patellar tendinopathy and a further improvement was noted at six months, after physiotherapy was added. Moreover, comparable results were obtained with respect to the less severe cases in the EQ VAS score and pain level evaluation, as in time to recover and patient satisfaction, with an even higher improvement in the sport activity level achieved in the PRP group. The clinical results are encouraging, indicating that PRP injections have the potential to promote the achievement of a satisfactory clinical outcome, even in difficult cases with chronic refractory tendinopathy after previous classical treatments have failed.

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Year:  2009        PMID: 19641918      PMCID: PMC2989009          DOI: 10.1007/s00264-009-0845-7

Source DB:  PubMed          Journal:  Int Orthop        ISSN: 0341-2695            Impact factor:   3.075


  24 in total

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2.  Effects of administration of transforming growth factor (TGF)-beta1 and anti-TGF-beta1 antibody on the mechanical properties of the stress-shielded patellar tendon.

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3.  Comparison of surgically repaired Achilles tendon tears using platelet-rich fibrin matrices.

Authors:  Mikel Sánchez; Eduardo Anitua; Juan Azofra; Isabel Andía; Sabino Padilla; Iñigo Mujika
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4.  Platelet-rich plasma enhances the initial mobilization of circulation-derived cells for tendon healing.

Authors:  Yoshiteru Kajikawa; Toru Morihara; Hirotaka Sakamoto; Ken-ichi Matsuda; Yasushi Oshima; Atsuhiko Yoshida; Masateru Nagae; Yuji Arai; Mitsuhiro Kawata; Toshikazu Kubo
Journal:  J Cell Physiol       Date:  2008-06       Impact factor: 6.384

5.  Platelet-rich plasma: new clinical application: a pilot study for treatment of jumper's knee.

Authors:  Elizaveta Kon; Giuseppe Filardo; Marco Delcogliano; Mirco Lo Presti; Alessandro Russo; Alice Bondi; Alessandro Di Martino; Annarita Cenacchi; Pier Maria Fornasari; Maurilio Marcacci
Journal:  Injury       Date:  2009-04-19       Impact factor: 2.586

6.  Treatment of chronic elbow tendinosis with buffered platelet-rich plasma.

Authors:  Allan Mishra; Terri Pavelko
Journal:  Am J Sports Med       Date:  2006-05-30       Impact factor: 6.202

7.  Medial epicondylitis: is ultrasound guided autologous blood injection an effective treatment?

Authors:  S P Suresh; K E Ali; H Jones; D A Connell
Journal:  Br J Sports Med       Date:  2006-09-21       Impact factor: 13.800

8.  The response of rabbit patellar tendons after autologous blood injection.

Authors:  Mark A Taylor; Timothy L Norman; Nina B Clovis; J David Blaha
Journal:  Med Sci Sports Exerc       Date:  2002-01       Impact factor: 5.411

9.  Ultrasound guided dry needling and autologous blood injection for patellar tendinosis.

Authors:  Steven L J James; Kaline Ali; Chris Pocock; Claire Robertson; Joy Walter; Jonathan Bell; David Connell
Journal:  Br J Sports Med       Date:  2007-03-26       Impact factor: 13.800

10.  Can platelet-rich plasma enhance tendon repair? A cell culture study.

Authors:  Marieke de Mos; Anna E van der Windt; Holger Jahr; Hans T M van Schie; Harrie Weinans; Jan A N Verhaar; Gerjo J V M van Osch
Journal:  Am J Sports Med       Date:  2008-03-07       Impact factor: 6.202

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  63 in total

Review 1.  Ultrasound-guided procedures to treat sport-related muscle injuries.

Authors:  Davide Orlandi; Angelo Corazza; Alice Arcidiacono; Carmelo Messina; Giovanni Serafini; Luca M Sconfienza; Enzo Silvestri
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2.  Lower Extremity Injury Patterns in Elite Ballet Dancers: Ultrasound/MRI Imaging Features and an Institutional Overview of Therapeutic Ultrasound Guided Percutaneous Interventions.

Authors:  Razia Rehmani; Yoshimi Endo; Phillip Bauman; William Hamilton; Hollis Potter; Ronald Adler
Journal:  HSS J       Date:  2015-07-10

Review 3.  Augmenting tendon and ligament repair with platelet-rich plasma (PRP).

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Journal:  Muscles Ligaments Tendons J       Date:  2013-08-11

Review 4.  Platelet-rich plasma in tendon-related disorders: results and indications.

Authors:  Giuseppe Filardo; Berardo Di Matteo; Elizaveta Kon; Giulia Merli; Maurilio Marcacci
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2016-09-24       Impact factor: 4.342

Review 5.  Spinal Cord Stimulation, MILD Procedure, and Regenerative Medicine, Novel Interventional Nonopioid Therapies in Chronic Pain.

Authors:  Ken P Ehrhardt; Susan M Mothersele; Andrew J Brunk; Jeremy B Green; Mark R Jones; Craig B Billeaud; Alan David Kaye
Journal:  Curr Pain Headache Rep       Date:  2018-03-19

6.  Platelet-rich plasma treatment improves outcomes for chronic proximal hamstring injuries in an athletic population.

Authors:  Ryan R Fader; Justin J Mitchell; Shaun Traub; Roger Nichols; Michelle Roper; Omer Mei Dan; Eric C McCarty
Journal:  Muscles Ligaments Tendons J       Date:  2015-02-05

7.  Application of Tendon Stem/Progenitor Cells and Platelet-Rich Plasma to Treat Tendon Injuries.

Authors:  James H-C Wang; Xavier Nirmala
Journal:  Oper Tech Orthop       Date:  2016-06

8.  Platelet-rich plasma injections for chronic plantar fasciitis.

Authors:  Nicolo Martinelli; Andrea Marinozzi; Stefano Carnì; Ugo Trovato; Alberto Bianchi; Vincenzo Denaro
Journal:  Int Orthop       Date:  2012-12-19       Impact factor: 3.075

9.  Plasma rich in growth factors (PRGF) as a treatment for high ankle sprain in elite athletes: a randomized control trial.

Authors:  Lior Laver; Michael R Carmont; Mark O McConkey; Ezequiel Palmanovich; Eyal Yaacobi; Gideon Mann; Meir Nyska; Eugene Kots; Omer Mei-Dan
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2014-06-18       Impact factor: 4.342

10.  Description of a standardized rehabilitation program based on sub-maximal eccentric following a platelet-rich plasma infiltration for jumper's knee.

Authors:  Jean-François Kaux; Bénédicte Forthomme; Marie-Hélène Namurois; Philippe Bauvir; Nathalie Defawe; François Delvaux; Cédric Lehance; Jean-Michel Crielaard; Jean-Louis Croisier
Journal:  Muscles Ligaments Tendons J       Date:  2014-05-08
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