Literature DB >> 19641815

Multicomponent reactions for the synthesis of multifunctional agents with activity against cancer cells.

Saad Shabaan1, Lalla A Ba, Muhammad Abbas, Torsten Burkholz, Annika Denkert, André Gohr, Ludger A Wessjohann, Florenz Sasse, Wolfgang Weber, Claus Jacob.   

Abstract

Multicomponent Passerini and Ugi reactions enable the fast and efficient synthesis of redox-active multifunctional selenium and tellurium compounds, of which some show considerable cytotoxicity against specific cancer cells.

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Year:  2009        PMID： 19641815     DOI： 10.1039/b823149d

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  7 in total

1.  One-pot organocatalytic/multicomponent approach for the preparation of novel enantioenriched non-natural selenium-based peptoids and peptide-peptoid conjugates.

Authors:  Alexander F de la Torre; Akbar Ali; Fábio Z Galetto; Antonio L Braga; José A C Delgado; Márcio W Paixão
Journal:  Mol Divers       Date:  2019-02-18       Impact factor: 2.943

2.  Synthesis of quinone imine and sulphur-containing compounds with antitumor and trypanocidal activities: redox and biological implications.

Authors:  Renata G Almeida; Wagner O Valença; Luísa G Rosa; Carlos A de Simone; Solange L de Castro; Juliana M C Barbosa; Daniel P Pinheiro; Carlos R K Paier; Guilherme G C de Carvalho; Claudia Pessoa; Marilia O F Goulart; Ammar Kharma; Eufrânio N da Silva Júnior
Journal:  RSC Med Chem       Date:  2020-07-13

Review 3.  Groebke-Blackburn-Bienaymé multicomponent reaction: emerging chemistry for drug discovery.

Authors:  Saad Shaaban; Bakr F Abdel-Wahab
Journal:  Mol Divers       Date:  2015-05-28       Impact factor: 2.943

4.  It takes two to tango: synthesis of cytotoxic quinones containing two redox active centers with potential antitumor activity.

Authors:  Daisy J B Lima; Renata G Almeida; Guilherme A M Jardim; Breno P A Barbosa; Augusto C C Santos; Wagner O Valença; Marcos R Scheide; Claudia C Gatto; Guilherme G C de Carvalho; Pedro M S Costa; Claudia Pessoa; Cynthia L M Pereira; Claus Jacob; Antonio L Braga; Eufrânio N da Silva Júnior
Journal:  RSC Med Chem       Date:  2021-08-12

5.  The organotelluride catalyst LAB027 prevents colon cancer growth in the mice.

Authors:  R Coriat; W Marut; M Leconte; L B Ba; A Vienne; C Chéreau; J Alexandre; B Weill; M Doering; C Jacob; C Nicco; F Batteux
Journal:  Cell Death Dis       Date:  2011-08-11       Impact factor: 8.469

6.  Mild and Expeditious Synthesis of Sulfenyl Enaminones of l-α-Amino Esters and Aryl/Alkyl Amines through NCS-Mediated Sulfenylation.

Authors:  Sayan Mukherjee; Animesh Pramanik
Journal:  ACS Omega       Date:  2021-11-30

7.  Synthesis and antitumor activity of selenium-containing quinone-based triazoles possessing two redox centres, and their mechanistic insights.

Authors:  Eduardo H G da Cruz; Molly A Silvers; Guilherme A M Jardim; Jarbas M Resende; Bruno C Cavalcanti; Igor S Bomfim; Claudia Pessoa; Carlos A de Simone; Giancarlo V Botteselle; Antonio L Braga; Divya K Nair; Irishi N N Namboothiri; David A Boothman; Eufrânio N da Silva Júnior
Journal:  Eur J Med Chem       Date:  2016-06-14       Impact factor: 6.514
  7 in total

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