Literature DB >> 1964049

Adaptive regulation of central serotonin receptors linked to phosphoinositide hydrolysis.

E Sanders-Bush1.   

Abstract

Central 5-HT2 and 5-HT1C receptors appear to be relatively resistant to up-regulation. 5-HT2 receptors are not upregulated after denervation of 5-HT neurons and chronic administration of antagonists elicits a paradoxical downregulation of both receptors. This article explores the possible explanations for these anomalous findings.

Mesh:

Substances:

Year:  1990        PMID: 1964049

Source DB:  PubMed          Journal:  Neuropsychopharmacology        ISSN: 0893-133X            Impact factor:   7.853


  6 in total

1.  Multiple 5-HT receptors in the guinea-pig superior cervical ganglion.

Authors:  C J Watkins; N R Newberry
Journal:  Br J Pharmacol       Date:  1996-01       Impact factor: 8.739

Review 2.  Conceptualizing the role of estrogens and serotonin in the development and maintenance of bulimia nervosa.

Authors:  Tom Hildebrandt; Lauren Alfano; Michelle Tricamo; Donald W Pfaff
Journal:  Clin Psychol Rev       Date:  2010-05-31

3.  Estimates of regional cerebral blood flow and 5-HT2A receptor density in impulsive, aggressive dogs with 99mTc-ECD and 123I-5-I-R91150.

Authors:  Kathelijne Peremans; Kurt Audenaert; Frank Coopman; Peter Blanckaert; Filip Jacobs; Andreas Otte; Francis Verschooten; Henri van Bree; Kees van Heeringen; John Mertens; Guido Slegers; Rudi Dierckx
Journal:  Eur J Nucl Med Mol Imaging       Date:  2003-07-03       Impact factor: 9.236

4.  Repeated administration of the novel antipsychotic olanzapine does not modulate NMDA-sensitive glutamate and 5HT2 serotonin receptors in rats.

Authors:  Ottavio Gandolfi; Manuela Voltattorni; Renato Gaggi; Rossella Dall'Olio
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2003-05-13       Impact factor: 3.000

5.  Effects of housing, restraint and chronic treatments with mCPP and sertraline on behavioural responses to mCPP.

Authors:  A J Kennedy; E L Gibson; M T O'Connell; G Curzon
Journal:  Psychopharmacology (Berl)       Date:  1993       Impact factor: 4.530

Review 6.  Phosphoinositide system-linked serotonin receptor subtypes and their pharmacological properties and clinical correlates.

Authors:  S C Pandey; J M Davis; G N Pandey
Journal:  J Psychiatry Neurosci       Date:  1995-05       Impact factor: 6.186

  6 in total

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