Seong Hyun Kim1, Ki Hwan Kim, Dong Soo Kim. 1. Department of Pediatrics, Severance Childrens Hospital, Yonsei University College of Medicine, 134 Shinchon-dong, Seodaemun-gu, Seoul 120-752, Korea.
Abstract
OBJECTIVE: We compared the clinical, laboratory and diagnostic features of Kawasaki disease (KD) in children <6 mo and >5 y of age to those in the more typical age range at diagnosis (6 mo-5 y of age). STUDY DESIGN: Retrospective analysis. SETTING: Severeance Children Hospital attached to a Medical School, Korea. METHODS: All children with a discharge diagnosis of KD at Severance Childrens Hospital (2006-2007) were retrospectively reviewed and grouped according to age at presentation in 3 groups: <6 mo, 6 mo-5 y and >5 years. Clinical, hematological, and biochemical features and involvement of coronary artery and proportion of Classic vs. Incomplete KD were compared between the 3 groups. RESULTS: A total of 185 children were identified. Complete KD was found in 63 (34%) children and Incomplete KD in 122 (66%). There was 22(12%) children below 6 months of age, 131 (71%) between 6 months to 5 years) and 32 (17%) above 5 years of age. Clinical, hematological and biochemical features were comparable between the three age groups. Overall, coronary artery lesions occurred in 9% children without any preference for age. The proportion of Classical vs. Incomplete KD was also similar in the three age categories. CONCLUSION: The clinical and laboratory phenotype of KD does not vary significantly with age.
OBJECTIVE: We compared the clinical, laboratory and diagnostic features of Kawasaki disease (KD) in children <6 mo and >5 y of age to those in the more typical age range at diagnosis (6 mo-5 y of age). STUDY DESIGN: Retrospective analysis. SETTING: Severeance Children Hospital attached to a Medical School, Korea. METHODS: All children with a discharge diagnosis of KD at Severance Childrens Hospital (2006-2007) were retrospectively reviewed and grouped according to age at presentation in 3 groups: <6 mo, 6 mo-5 y and >5 years. Clinical, hematological, and biochemical features and involvement of coronary artery and proportion of Classic vs. Incomplete KD were compared between the 3 groups. RESULTS: A total of 185 children were identified. Complete KD was found in 63 (34%) children and Incomplete KD in 122 (66%). There was 22(12%) children below 6 months of age, 131 (71%) between 6 months to 5 years) and 32 (17%) above 5 years of age. Clinical, hematological and biochemical features were comparable between the three age groups. Overall, coronary artery lesions occurred in 9% children without any preference for age. The proportion of Classical vs. Incomplete KD was also similar in the three age categories. CONCLUSION: The clinical and laboratory phenotype of KD does not vary significantly with age.