Literature DB >> 19637917

Corallolides A and B: bioactive diterpenes featuring a novel carbon skeleton.

Claudia A Ospina1, Abimael D Rodríguez.   

Abstract

Corallolides A (1) and B (2) are naturally occurring diterpenes isolated from the Caribbean gorgonian octocoral Pseudopterogorgia bipinnata collected near Providencia Island, Colombia. Their tricyclic structures are based on a uniquely substituted bicyclo[9.2.1]tetradecane ring system that was established through detailed spectroscopic analysis. Compounds 1 and 2 were shown to exhibit antiparasitic and antituberculosis activity, respectively.

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Year:  2009        PMID: 19637917      PMCID: PMC2740495          DOI: 10.1021/ol901577a

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  4 in total

Review 1.  Marine natural products.

Authors:  John W Blunt; Brent R Copp; Wan-Ping Hu; Murray H G Munro; Peter T Northcote; Michèle R Prinsep
Journal:  Nat Prod Rep       Date:  2009-01-06       Impact factor: 13.423

Review 2.  The chemistry of marine furanocembranoids, pseudopteranes, gersolanes, and related natural products.

Authors:  Paul A Roethle; Dirk Trauner
Journal:  Nat Prod Rep       Date:  2008-02-25       Impact factor: 13.423

Review 3.  Diterpenes from gorgonian corals.

Authors:  Fabrice Berrue; Russell G Kerr
Journal:  Nat Prod Rep       Date:  2009-03-25       Impact factor: 13.423

Review 4.  Marine soft corals of the genus Pseudopterogorgia: a resource for novel anti-inflammatory diterpenoids.

Authors:  W Fenical
Journal:  J Nat Prod       Date:  1987 Nov-Dec       Impact factor: 4.050

  4 in total
  2 in total

Review 1.  The structural diversity and promise of antiparasitic marine invertebrate-derived small molecules.

Authors:  Katharine R Watts; Karen Tenney; Phillip Crews
Journal:  Curr Opin Biotechnol       Date:  2010-10-16       Impact factor: 9.740

2.  Selective syntheses of Δ(α,β) and Δ(β,γ) butenolides from allylic cyclopropenecarboxylates via tandem ring expansion/[3,3]-sigmatropic rearrangements.

Authors:  Xiaocong Xie; Yi Li; Joseph M Fox
Journal:  Org Lett       Date:  2013-03-20       Impact factor: 6.005

  2 in total

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