Literature DB >> 19636914

NMR assignment of the C-terminal actin-binding domain of talin.

Benjamin T Goult1, Alexandre R Gingras, Neil Bate, Gordon C K Roberts, David R Critchley, Igor L Barsukov.   

Abstract

Talin is a large dimeric 270 kDa adapter protein which binds the cytoplasmic face of a subset of integrin beta-subunits and couples them to the actin cytoskeleton. Here we report the near complete 15N, 13C and 1H chemical shift assignments for the C-terminal actin-binding domain.

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Year:  2007        PMID: 19636914     DOI: 10.1007/s12104-007-9073-5

Source DB:  PubMed          Journal:  Biomol NMR Assign        ISSN: 1874-270X            Impact factor:   0.746


  2 in total

1.  The domain structure of talin: residues 1815-1973 form a five-helix bundle containing a cryptic vinculin-binding site.

Authors:  Benjamin T Goult; Alexandre R Gingras; Neil Bate; Igor L Barsukov; David R Critchley; Gordon C K Roberts
Journal:  FEBS Lett       Date:  2010-04-20       Impact factor: 4.124

2.  RIAM and vinculin binding to talin are mutually exclusive and regulate adhesion assembly and turnover.

Authors:  Benjamin T Goult; Thomas Zacharchenko; Neil Bate; Ricky Tsang; Fiona Hey; Alexandre R Gingras; Paul R Elliott; Gordon C K Roberts; Christoph Ballestrem; David R Critchley; Igor L Barsukov
Journal:  J Biol Chem       Date:  2013-02-06       Impact factor: 5.157

  2 in total

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