Literature DB >> 1963659

Cation transport probes: the amiloride series.

T R Kleyman, E J Cragoe.   

Abstract

The use of amiloride and its analogs in the study of ion transport requires a knowledge of the pharmacology of inhibition of transport proteins, and of effects on enzymes, receptors, and other cellular processes, such as DNA, RNA, and protein synthesis, and cellular metabolism. We have reviewed the pharmacology of inhibition of these processes by amiloride an its analogs, as well as the use of amiloride analogs as potential probes for the characterization of ion transport systems.

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Year:  1990        PMID: 1963659     DOI: 10.1016/0076-6879(90)91045-8

Source DB:  PubMed          Journal:  Methods Enzymol        ISSN: 0076-6879            Impact factor:   1.600


  18 in total

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