Perineurioma of esophagus: a first case report.

Benign peripheral nerve sheath tumors occur uncommonly in the gastrointestinal (GI) tract. Perineurioma located in the GI tract is an extremely rare entity, and only 14 cases have been reported in colon, 1 in jejunum, and 1 in stomach. However, perineurioma of the esophagus presenting with dysphagia has not been reported before, and we describe, to our knowledge, the first case in the literature. We suggest that localization of such submucosal tumors can be challenging, and injection of the lesion with dye preoperatively can increase the chances of localization and successful resection of such tumors. Perineuriomas should be included in the complete differential diagnosis of GI tumors.