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Literature DB >> 19633961

The revolution of epigenetics in the field of autoimmunity.

Abstract

Autoimmunity is believed to develop when genetically predisposed individuals encounter epigenetic modifications in response to environmental factors. Recent advances in the understanding of epigenetic mechanisms, their contribution to the immune function, and to the development of autoimmunity are presented in this special issue of Clinical Reviews in Allergy and Immunology. Potential new therapeutic strategies and biomarkers are also addressed.

Entities: Disease

Mesh：

Substances：
Biomarkers

Year: 2010 PMID： 19633961 DOI： 10.1007/s12016-009-8171-9

Source DB: PubMed Journal: Clin Rev Allergy Immunol ISSN： 1080-0549 Impact factor: 8.667

14 in total

Review 1. The epigenetic face of systemic lupus erythematosus.

Authors: Esteban Ballestar; Manel Esteller; Bruce C Richardson
Journal: J Immunol Date: 2006-06-15 Impact factor: 5.422

2. Epigenetic differences arise during the lifetime of monozygotic twins.

Authors: Mario F Fraga; Esteban Ballestar; Maria F Paz; Santiago Ropero; Fernando Setien; Maria L Ballestar; Damia Heine-Suñer; Juan C Cigudosa; Miguel Urioste; Javier Benitez; Manuel Boix-Chornet; Abel Sanchez-Aguilera; Charlotte Ling; Emma Carlsson; Pernille Poulsen; Allan Vaag; Zarko Stephan; Tim D Spector; Yue-Zhong Wu; Christoph Plass; Manel Esteller
Journal: Proc Natl Acad Sci U S A Date: 2005-07-11 Impact factor: 11.205

The revolution of epigenetics in the field of autoimmunity.

Review 1. The epigenetic face of systemic lupus erythematosus.

2. Epigenetic differences arise during the lifetime of monozygotic twins.

Review 3. Female predominance and X chromosome defects in autoimmune diseases.

4. IL-6 modulates CD5 expression in B cells from patients with lupus by regulating DNA methylation.

Review 5. The genetics and epigenetics of autoimmune diseases.

Review 6. Primary Ovarian Insufficiency: X chromosome defects and autoimmunity.

Review 7. Understanding what determines the frequency and pattern of human germline mutations.

8. Autoimmune stigmata in Turner syndrome: when lacks an X chromosome.

Review 9. Future directions in genetic for autoimmune diseases.

Review 10. Making a firm decision: multifaceted regulation of cell fate in the early mouse embryo.

1. Novel challenges for the allergist.

2. Cutting-edge issues in organ-specific autoimmunity.

Review 3. The autoimmune side of heart and lung diseases.

Review 4. The long-term marriage between autoimmunity and internal medicine: a homage to Manuel Carlos Dias.

5. The future of autoimmunity.

6. Decrease in alpha-1 antiproteinase antitrypsin is observed in primary Sjogren's syndrome condition.

Review 7. The contribution of epigenetics in Sjögren's Syndrome.

8. Rheumatoid arthritis and primary biliary cirrhosis: cause, consequence, or coincidence?