Literature DB >> 19632170

Cell death: a new Par-4 the TRAIL.

Lori S Hart1, Wafik S El-Deiry.   

Abstract

The protein Par-4 acts in the cytoplasm to trigger cell death signaling via caspase activation and the mitochondrial release of cytochrome c. Burikhanov et al. (2009) now provide surprising evidence that Par-4 can also promote apoptosis from outside the cell, after its secretion in response to endoplasmic reticulum stress.

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Year:  2009        PMID： 19632170     DOI： 10.1016/j.cell.2009.07.007

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  5 in total

1.  Prostate Apoptosis Response-4 (Par-4): A Novel Target in Pyronaridine-Induced Apoptosis in Glioblastoma (GBM) Cells.

Authors:  Jeevan Ghosalkar; Vinay Sonawane; Tejal Pisal; Swati Achrekar; Radha Pujari; Ashish Chugh; Padma Shastry; Kalpana Joshi
Journal:  Cancers (Basel)       Date:  2022-06-29       Impact factor: 6.575

Review 2.  A journey beyond apoptosis: new enigma of controlling metastasis by pro-apoptotic Par-4.

Authors:  Reyaz Ur Rasool; Debasis Nayak; Souneek Chakraborty; Archana Katoch; Mir Mohd Faheem; Hina Amin; Anindya Goswami
Journal:  Clin Exp Metastasis       Date:  2016-08-27       Impact factor: 5.150

3.  The Par-4-GRP78 TRAIL, more twists and turns.

Authors:  Amy S Lee
Journal:  Cancer Biol Ther       Date:  2009-11-20       Impact factor: 4.742

Review 4.  Targeting apoptosis in cancer therapy.

Authors:  Benedito A Carneiro; Wafik S El-Deiry
Journal:  Nat Rev Clin Oncol       Date:  2020-03-23       Impact factor: 66.675

5.  IRES-Dependent Translational Control during Virus-Induced Endoplasmic Reticulum Stress and Apoptosis.

Authors:  Paul J Hanson; Huifang M Zhang; Maged Gomaa Hemida; Xin Ye; Ye Qiu; Decheng Yang
Journal:  Front Microbiol       Date:  2012-03-19       Impact factor: 5.640
  5 in total

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