Literature DB >> 19631480

Life style interventions to reduce the risk of dementia.

Leon Flicker1.   

Abstract

Dementia has often thought to be unavoidable and incurable. In recent years, risk factors, including lifestyle attributes, have been associated with the two commonest forms of dementia, Alzheimer's Disease and vascular dementia. There is also new evidence that the adult brain maintains plasticity and response to external stimuli. Beside considerable observational data of the effect of lifestyle factors there is now increasing empirical evidence that alterations in lifestyle factors may decrease an individual's risk of developing dementia. The evidence is strongest for increasing an individual's level of physical activity, followed by the cessation of smoking. These interventions carry few risks and have many additional health benefits, so can be recommended for most of the older population. Other interventions such as increasing social engagement, cognitive stimulation and homocysteine lowering vitamin supplements also appear promising, with considerable observational evidence supporting their uptake, although there is still a lack of empirical evidence for these interventions.

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Year:  2009        PMID: 19631480     DOI: 10.1016/j.maturitas.2009.06.008

Source DB:  PubMed          Journal:  Maturitas        ISSN: 0378-5122            Impact factor:   4.342


  6 in total

Review 1.  Vascular basis for brain degeneration: faltering controls and risk factors for dementia.

Authors:  Raj N Kalaria
Journal:  Nutr Rev       Date:  2010-12       Impact factor: 7.110

2.  History of lifetime smoking, smoking cessation and cognitive function in the elderly population.

Authors:  Ute Mons; Ben Schöttker; Heiko Müller; Matthias Kliegel; Hermann Brenner
Journal:  Eur J Epidemiol       Date:  2013-08-30       Impact factor: 8.082

Review 3.  Physical activity and mild cognitive impairment and Alzheimer's disease.

Authors:  Nicola T Lautenschlager; Kay Cox; Alexander F Kurz
Journal:  Curr Neurol Neurosci Rep       Date:  2010-09       Impact factor: 5.081

4.  Plasticity in Early Alzheimer's Disease: An Opportunity for Intervention.

Authors:  Nikki L Hill; Ann M Kolanowski; David J Gill
Journal:  Top Geriatr Rehabil       Date:  2011-10

5.  The Agewell trial: a pilot randomised controlled trial of a behaviour change intervention to promote healthy ageing and reduce risk of dementia in later life.

Authors:  Linda Clare; Sharon M Nelis; Ian R Jones; John V Hindle; Jeanette M Thom; Julie A Nixon; Jennifer Cooney; Carys L Jones; Rhiannon Tudor Edwards; Christopher J Whitaker
Journal:  BMC Psychiatry       Date:  2015-02-19       Impact factor: 3.630

Review 6.  Role of Sleep Disturbance in the Trajectory of Alzheimer's Disease.

Authors:  Dong Woo Kang; Chang Uk Lee; Hyun Kook Lim
Journal:  Clin Psychopharmacol Neurosci       Date:  2017-05-31       Impact factor: 2.582

  6 in total

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