Literature DB >> 19630042

Selective identification of cooperatively binding fragments in a high-throughput ligation assay enables development of a picomolar caspase-3 inhibitor.

Marco F Schmidt1, Adeeb El-Dahshan, Sandro Keller, Jörg Rademann.   

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Year:  2009        PMID： 19630042     DOI： 10.1002/anie.200901647

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


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  14 in total

1.  Nonlinear least-squares data fitting in Excel spreadsheets.

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Journal:  Nat Protoc       Date:  2010-01-28       Impact factor: 13.491

2.  A fluorescent target-guided Paal-Knorr reaction.

Authors:  Sachin B Wagh; Vladimir Maslivetc; James J La Clair; Alexander Kornienko
Journal:  RSC Adv       Date:  2020-10-07       Impact factor: 4.036

3.  Fragment Linking and Optimization of Inhibitors of the Aspartic Protease Endothiapepsin: Fragment-Based Drug Design Facilitated by Dynamic Combinatorial Chemistry.

Authors:  Milon Mondal; Nedyalka Radeva; Hugo Fanlo-Virgós; Sijbren Otto; Gerhard Klebe; Anna K H Hirsch
Journal:  Angew Chem Int Ed Engl       Date:  2016-07-12       Impact factor: 15.336

4.  Protein-Templated Formation of an Inhibitor of the Blood Coagulation Factor Xa through a Background-Free Amidation Reaction.

Authors:  Mike Jaegle; Torsten Steinmetzer; Jörg Rademann
Journal:  Angew Chem Int Ed Engl       Date:  2017-02-15       Impact factor: 15.336

5.  Identification of β-strand mediated protein-protein interaction inhibitors using ligand-directed fragment ligation.

Authors:  Zsófia Hegedüs; Fruzsina Hóbor; Deborah K Shoemark; Sergio Celis; Lu-Yun Lian; Chi H Trinh; Richard B Sessions; Thomas A Edwards; Andrew J Wilson
Journal:  Chem Sci       Date:  2021-01-06       Impact factor: 9.825

6.  N-[(E)-4-Bromo-benzyl-idene]-3,4-di-methyl-aniline.

Authors:  Li-Xia Sun; Ling-Zhi Zhu; Jun-Kai Wang
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2013-04-05

7.  Mechanistic and structural understanding of uncompetitive inhibitors of caspase-6.

Authors:  Christopher E Heise; Jeremy Murray; Katherine E Augustyn; Brandon Bravo; Preeti Chugha; Frederick Cohen; Anthony M Giannetti; Paul Gibbons; Rami N Hannoush; Brian R Hearn; Priyadarshini Jaishankar; Cuong Q Ly; Kinjalkumar Shah; Karen Stanger; Micah Steffek; Yinyan Tang; Xianrui Zhao; Joseph W Lewcock; Adam R Renslo; John Flygare; Michelle R Arkin
Journal:  PLoS One       Date:  2012-12-05       Impact factor: 3.240

8.  N-[(E)-4-Bromo-benzyl-idene]-2,3-di-methyl-aniline.

Authors:  Li-Xia Sun; Ling-Zhi Zhu; Jun-Kai Wang
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2013-04-05

9.  Irreversible inhibitors of the 3C protease of Coxsackie virus through templated assembly of protein-binding fragments.

Authors:  Daniel Becker; Zuzanna Kaczmarska; Christoph Arkona; Robert Schulz; Carolin Tauber; Gerhard Wolber; Rolf Hilgenfeld; Miquel Coll; Jörg Rademann
Journal:  Nat Commun       Date:  2016-09-28       Impact factor: 14.919

10.  High-Throughput Kinetic Analysis for Target-Directed Covalent Ligand Discovery.

Authors:  Gregory B Craven; Dominic P Affron; Charlotte E Allen; Stefan Matthies; Joe G Greener; Rhodri M L Morgan; Edward W Tate; Alan Armstrong; David J Mann
Journal:  Angew Chem Int Ed Engl       Date:  2018-03-26       Impact factor: 15.336
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