Literature DB >> 19629304

Small ventricular septal defect: long-term expectant clinical management.

Edmar Atik1.   

Abstract

BACKGROUND: The small ventricular septal defect (VSD) usually presents good clinical evolution, even at long-term follow-up.
OBJECTIVE: To verify the clinical evolution of patients with small VSD in order to determine the continuation or not of the expectant conduct, considering the low operative risk, which results in a more liberal indication for surgery.
METHODS: From October 1976 to December 2007, 187 cases of small VSD (diameter < 3 mm at the echocardiogram) were evaluated and 155 of them were assessed at long-term follow-up. Time of the clinical manifestation of the murmur and evolution aspects such as the spontaneous closure of the defect (group I)--64 cases, persistence of the initial size (group II--74 cases and decrease in the size of the defect (group III)--17 cases, in addition to clinical complications, were studied.
RESULTS: The clinical manifestation of the murmur occurred, in the majority of cases, during the first month of life, corresponding to 48 (75%), 54 (72.9%) and 12 (70.5%) patients, in the three groups, respectively and after the first year of life in 11 (5.8%) patients. Spontaneous closure occurred in the first year of life in 48 cases (75%), mean of 7.6 months and from 1 to 5.5 years in 15 patients (23.4%), with a maximum follow-up of 18 years. The persistence of the defect until 40 years of age was observed. The decrease in the size of the defect occurred on a mean of 15 months, followed for up to 9 years. The probability of VSD closure by the actuarial curve was 34.38% in 1 year and 49.89% in 5 years. There were no clinical complications.
CONCLUSION: A favorable evolution of the small VSD at long-term follow-up does not require surgical intervention, with concerns regarding the strict antibiotic prophylaxis.

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Year:  2009        PMID: 19629304     DOI: 10.1590/s0066-782x2009000600003

Source DB:  PubMed          Journal:  Arq Bras Cardiol        ISSN: 0066-782X            Impact factor:   2.000


  5 in total

1.  Case 6/2016 - The Patient is a 29-Year-Old Male with Spontaneous Closure of Ventricular Septal Defect in Adulthood.

Authors:  Edmar Atik
Journal:  Arq Bras Cardiol       Date:  2016-10       Impact factor: 2.000

2.  Factors influencing the spontaneous closure of ventricular septal defect in infants.

Authors:  Yang Xu; Jinxiang Liu; Jinghua Wang; Min Liu; Hui Xu; Sirui Yang
Journal:  Int J Clin Exp Pathol       Date:  2015-05-01

Review 3.  A review of cardiopulmonary research in Brazilian medical journals: clinical, surgical and epidemiological data.

Authors:  Carlos Serrano; Mauricio Rocha e Silva
Journal:  Clinics (Sao Paulo)       Date:  2010-04       Impact factor: 2.365

4.  Subspecialty surveillance of long-term course of small and moderate muscular ventricular septal defect: heterogenous practices, low yield.

Authors:  Erik L Frandsen; Aswathy V House; Yunbin Xiao; David A Danford; Shelby Kutty
Journal:  BMC Pediatr       Date:  2014-11-04       Impact factor: 2.125

5.  Prediction of spontaneous closure of isolated ventricular septal defects in utero and postnatal life.

Authors:  Xing Li; Gui-Xian Song; Li-Jie Wu; Yu-Mei Chen; Yi Fan; Yun Wu; Ya-Hui Shen; Li Cao; Ling-Mei Qian
Journal:  BMC Pediatr       Date:  2016-12-08       Impact factor: 2.125

  5 in total

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