Literature DB >> 19628932

Prediction of mortality in elderly patients with hip fractures: a two-year prospective study of 1,944 patients.

Anita Söderqvist1, Wilhelmina Ekström, Sari Ponzer, Hans Pettersson, Tommy Cederholm, Nils Dalén, Margareta Hedström, Jan Tidermark.   

Abstract

BACKGROUND: Hip fracture patients are reported to have an increased mortality rate compared to the general population. In order to be able to reduce the morbidity and mortality after a hip fracture, our efforts to identify the patients at risk already upon admission to the hospital need to be increased. For such a risk assessment, robust, validated, and reproducible criteria are mandatory.
OBJECTIVE: To determine preoperative factors associated with mortality and to evaluate the combined use of the American Society of Anesthesiologists (ASA) and the Short Portable Mental Status Questionnaire (SPMSQ) to identify patients with an increased mortality rate and to create a predictive model to assess the mortality risk after hip fracture surgery.
METHODS: A total of 1,944 consecutive patients aged 66 years or older admitted for a hip fracture were included in a prospective cohort study with a 24-month follow-up. The patients were assessed with regard to gender, age, type of hip fracture, smoking habits, comorbidities, general physical health according to the ASA classification, and cognitive function according to the SPMSQ. A higher ASA score indicates an increasingly severe systemic disease and a lower SPMSQ score indicates an increasingly severe cognitive dysfunction. We used Cox proportional hazard models and classification trees to identify the factors associated with mortality. The predictive model was created based on factors that were significantly associated with death and all readily accessible upon admission.
RESULTS: The mortality rate during the acute hospitalization period was 4%, at 4 months 16%, and at 24 months 38%. The most prominent factors associated with mortality were high ASA scores, low SPMSQ scores, high age and male gender. The SPMSQ score provided additional information about the survival time, compared to when the ASA score was used alone.
CONCLUSION: The combined use of the ASA classification for assessing physical health and the SPMSQ for assessing cognitive function effectively identified hip fracture patients with an increased mortality rate. We present a predictive model including age, gender, ASA, and SPMSQ that can be used to assess the mortality risk after hip fracture surgery. Copyright 2009 S. Karger AG, Basel.

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Mesh:

Year:  2009        PMID: 19628932     DOI: 10.1159/000230587

Source DB:  PubMed          Journal:  Gerontology        ISSN: 0304-324X            Impact factor:   5.140


  42 in total

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Review 2.  [Procedural organisation: surgical and anaesthesiological management in hip fractures].

Authors:  Ernst J Müller; Ingeborg Gerstorfer; Peter Dovjak; Bernhard Iglseder; Georg Pinter; Walter Müller; Katharina Pils; Peter Mikosch; Michaela Zmaritz; Monique Weissenberger-Leduc; Markus Gosch; Heinrich W Thaler
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3.  Unipolar hemiarthroplasty versus bipolar hemiarthroplasty in the most elderly patients with displaced femoral neck fractures: a randomised, controlled trial.

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Journal:  Int Orthop       Date:  2011-02-08       Impact factor: 3.075

4.  Excess mortality following hip fracture: impact of self-perceived health, smoking, and body mass index. A NOREPOS study.

Authors:  S M Solbakken; H E Meyer; H Stigum; A J Søgaard; K Holvik; J H Magnus; T K Omsland
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Authors:  Chieh Yang Koo; Joseph A Hyder; Jonathan P Wanderer; Matthias Eikermann; Satya Krishna Ramachandran
Journal:  World J Surg       Date:  2015-01       Impact factor: 3.352

Review 6.  Proton pump inhibitors and fracture risk: true effect or residual confounding?

Authors:  Michael Bodmer; Christian Meier; Marius E Kraenzlin; Christoph R Meier
Journal:  Drug Saf       Date:  2010-10-01       Impact factor: 5.606

7.  Examining heterogeneity of functional recovery among older adults with hip fractures.

Authors:  Yuchi Young; Kuangnan Xiong; Robert M Pruzek; Larry J Brant
Journal:  J Am Med Dir Assoc       Date:  2010-01-15       Impact factor: 4.669

8.  Effects of abaloparatide on bone mineral density and risk of fracture in postmenopausal women aged 80 years or older with osteoporosis.

Authors:  Michael R McClung; Nicholas C Harvey; Lorraine A Fitzpatrick; Paul D Miller; Gary Hattersley; Yamei Wang; Felicia Cosman
Journal:  Menopause       Date:  2018-07       Impact factor: 2.953

9.  Fractures and Subsequent Graft Loss and Mortality among Older Kidney Transplant Recipients.

Authors:  Megan L Salter; Xinran Liu; Sunjae Bae; Nadia M Chu; Alexandra Miller Dunham; Casey Humbyrd; Dorry L Segev; Mara A McAdams-DeMarco
Journal:  J Am Geriatr Soc       Date:  2019-05-06       Impact factor: 5.562

10.  Pre-fracture quality of life predicts 1-year survival in elderly patients with hip fracture-development of a new scoring system.

Authors:  C Bliemel; R Sielski; B Doering; R Dodel; M Balzer-Geldsetzer; S Ruchholtz; B Buecking
Journal:  Osteoporos Int       Date:  2016-01-05       Impact factor: 4.507

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