| Literature DB >> 19628388 |
Kyung-Hee Kim1, Allan Wissner, Middleton B Floyd, Heidi L Fraser, Yanong D Wang, Russell G Dushin, Yongbo Hu, Andrea Olland, Bing Guo, Kim Arndt.
Abstract
A series of substituted benzo[c][2,7]-naphthyridines were prepared and showed good potency in inhibiting PDK-1. The synthesis and SAR of this series of compounds are presented as well as the X-ray crystal structure of one of these analogs in a complex with PDK-1.Entities:
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Year: 2009 PMID： 19628388 DOI： 10.1016/j.bmcl.2009.07.007
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823