Literature DB >> 19627901

VA-based survey of osteoporosis management in spinal cord injury.

Leslie R Morse1, Lora Giangregorio, Ricardo A Battaglino, Robert Holland, B Catharine Craven, Kelly L Stolzmann, Antonio A Lazzari, Sunil Sabharwal, Eric Garshick.   

Abstract

OBJECTIVE: Although osteoporosis is common following spinal cord injury (SCI), no guidelines exist for its treatment, diagnosis, or prevention. The authors hypothesized that wide variations in diagnosis and treatment practices result from the absence of guidelines. This study sought to characterize the diagnosis and management practices within the VA health care system for osteoporosis following SCI.
DESIGN: Online survey regarding osteoporosis management in SCI composed of 27 questions designed to gather information on responder demographics, osteoporosis diagnostics, and treatment options.
SETTING: VA health care system. PARTICIPANTS: VHA National SCI Staff Physicians and VHA National SCI Nurses (total n = 450) were sent an email with an invitation to participate. INTERVENTION: Not applicable. MAIN OUTCOME MEASURES: Practice patterns were assessed, including factors associated with ordering a clinical workup and prescribing osteoporosis treatment.
RESULTS: The response rate was 28%. Ninety-two prescribing practitioners (physicians, nurse practitioners, and physician assistants) were included in the analysis. Of these respondents, 50 (54%) prescribe medications for SCI-induced bone loss; 39 (42%) prescribe bisphosphonates and 46 (50%) prescribe vitamin D. There were 54 (59%) respondents who routinely order diagnostic tests, including dual energy x-ray absorptiometry scans in 50 (54%). Variations in practice were not explained by age, gender, or years practicing SCI medicine. Many respondents (23%) reported barriers to osteoporosis testing including lack of scanning protocols, cost, wheelchair inaccessibility of scanning facilities, and lack of effective treatment guidelines once osteoporosis is diagnosed.
CONCLUSIONS: Despite an absence of screening and treatment guidelines, more than half of all respondents are actively diagnosing and treating osteoporosis with bisphosphonates within the VA health care setting. These data suggest that evidence-based practice guidelines are necessary to reduce practice variations and improve clinical care for this population.

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Year:  2009        PMID: 19627901      PMCID: PMC2791704          DOI: 10.1016/j.pmrj.2008.10.008

Source DB:  PubMed          Journal:  PM R        ISSN: 1934-1482            Impact factor:   2.298


  26 in total

1.  Bone mineral density differences between paraplegic and quadriplegic patients: a cross-sectional study.

Authors:  S Tsuzuku; Y Ikegami; K Yabe
Journal:  Spinal Cord       Date:  1999-05       Impact factor: 2.772

2.  Longitudinal changes in bone in men with spinal cord injury.

Authors:  E D de Bruin; V Dietz; M A Dambacher; E Stüssi
Journal:  Clin Rehabil       Date:  2000-04       Impact factor: 3.477

3.  Extremity fractures of patients with spinal cord injuries.

Authors:  A E COMARR; R H HUTCHINSON; E BORS
Journal:  Am J Surg       Date:  1962-06       Impact factor: 2.565

4.  Long-term changes in the tibia and radius bone mineral density following spinal cord injury.

Authors:  E D de Bruin; B Vanwanseele; M A Dambacher; V Dietz; E Stüssi
Journal:  Spinal Cord       Date:  2005-02       Impact factor: 2.772

5.  Alendronate prevents bone loss in patients with acute spinal cord injury: a randomized, double-blind, placebo-controlled study.

Authors:  N L Gilchrist; C M Frampton; R H Acland; M G Nicholls; R L March; P Maguire; A Heard; P Reilly; K Marshall
Journal:  J Clin Endocrinol Metab       Date:  2007-01-16       Impact factor: 5.958

6.  Longitudinal study of bone mineral content in the lumbar spine, the forearm and the lower extremities after spinal cord injury.

Authors:  F Biering-Sørensen; H H Bohr; O P Schaadt
Journal:  Eur J Clin Invest       Date:  1990-06       Impact factor: 4.686

7.  Changes of tibia bone properties after spinal cord injury: effects of early intervention.

Authors:  E D de Bruin; P Frey-Rindova; R E Herzog; V Dietz; M A Dambacher; E Stüssi
Journal:  Arch Phys Med Rehabil       Date:  1999-02       Impact factor: 3.966

8.  Determinants of bone mineral density in immobilization: a study on hemiplegic patients.

Authors:  A del Puente; N Pappone; M G Mandes; D Mantova; R Scarpa; P Oriente
Journal:  Osteoporos Int       Date:  1996       Impact factor: 4.507

9.  Osteoporotic fractures and hospitalization risk in chronic spinal cord injury.

Authors:  L R Morse; R A Battaglino; K L Stolzmann; L D Hallett; A Waddimba; D Gagnon; A A Lazzari; E Garshick
Journal:  Osteoporos Int       Date:  2008-06-26       Impact factor: 4.507

10.  Fracture rates and risk factors for fractures in patients with spinal cord injury.

Authors:  P Vestergaard; K Krogh; L Rejnmark; L Mosekilde
Journal:  Spinal Cord       Date:  1998-11       Impact factor: 2.772

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  20 in total

1.  Association between sclerostin and bone density in chronic spinal cord injury.

Authors:  Leslie R Morse; Supreetha Sudhakar; Valery Danilack; Carlos Tun; Antonio Lazzari; David R Gagnon; Eric Garshick; Ricardo A Battaglino
Journal:  J Bone Miner Res       Date:  2012-02       Impact factor: 6.741

Review 2.  Bone Imaging and Fracture Risk after Spinal Cord Injury.

Authors:  W Brent Edwards; Thomas J Schnitzer
Journal:  Curr Osteoporos Rep       Date:  2015-10       Impact factor: 5.096

3.  Predicting osteoporosis medication receipt in Veterans with a spinal cord injury: A retrospective cohort study.

Authors:  Frances M Weaver; Brian Le; Cara Ray; Scott Miskevics; Beverly Gonzalez; Laura D Carbone
Journal:  J Spinal Cord Med       Date:  2019-03-19       Impact factor: 1.985

4.  Severe Spinal Cord Injury Causes Immediate Multi-cellular Dysfunction at the Chondro-Osseous Junction.

Authors:  Leslie R Morse; Yan Xu; Bethlehem Solomon; Lara Boyle; Subbiah Yoganathan; Philip Stashenko; Ricardo A Battaglino
Journal:  Transl Stroke Res       Date:  2011-12-01       Impact factor: 6.829

5.  Sclerostin: a candidate biomarker of SCI-induced osteoporosis.

Authors:  L R Morse; S Sudhakar; A A Lazzari; C Tun; E Garshick; R Zafonte; R A Battaglino
Journal:  Osteoporos Int       Date:  2012-07-17       Impact factor: 4.507

6.  Wheelchair use and lipophilic statin medications may influence bone loss in chronic spinal cord injury: findings from the FRASCI-bone loss study.

Authors:  L R Morse; N Nguyen; R A Battaglino; A J Guarino; D R Gagnon; R Zafonte; E Garshick
Journal:  Osteoporos Int       Date:  2016-07-13       Impact factor: 4.507

Review 7.  Chronic complications of spinal cord injury.

Authors:  Nebahat Sezer; Selami Akkuş; Fatma Gülçin Uğurlu
Journal:  World J Orthop       Date:  2015-01-18

8.  Risk factors for osteoporotic fractures in persons with spinal cord injuries and disorders.

Authors:  M Bethel; F M Weaver; L Bailey; S Miskevics; J N Svircev; S P Burns; H Hoenig; K Lyles; L D Carbone
Journal:  Osteoporos Int       Date:  2016-05-26       Impact factor: 4.507

9.  Metasynthesis of Patient Attitudes Toward Bone Densitometry.

Authors:  Aaron T Seaman; Melissa Steffen; Taisha Doo; Heather S Healy; Samantha L Solimeo
Journal:  J Gen Intern Med       Date:  2018-07-27       Impact factor: 5.128

Review 10.  Spinal cord injury-induced osteoporosis: pathogenesis and emerging therapies.

Authors:  Ricardo A Battaglino; Antonio A Lazzari; Eric Garshick; Leslie R Morse
Journal:  Curr Osteoporos Rep       Date:  2012-12       Impact factor: 5.096

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