| Literature DB >> 19626270 |
Christine Capper-Loup1, Dominik Rebell, Alain Kaelin-Lang.
Abstract
Little is known about hemispheric lateralization of subcortical structures. Here, we show a higher expression of the subunit NR2A of the NMDA receptor mRNA in the striatum and of vGluT1 mRNA in the cingulate cortex, in the left hemisphere compared to the right one. This suggests a lateralization of the glutamatergic cortico-subcortical system, at the level of postsynaptic receptors as well as at the level of corticostriatal projections. Such lateralization could play a role in asymmetric diseases like Parkinson's disease.Entities:
Mesh：
Substances：
Year: 2009 PMID： 19626270 DOI： 10.1007/s00702-009-0265-2
Source DB: PubMed Journal: J Neural Transm (Vienna) ISSN： 0300-9564 Impact factor: 3.575