Literature DB >> 19626055

A fine balance: an autoregulatory gene therapy approach to treat obesity and achieve energy homeostasis.

S L Samson, M Kohjima, L Chan.   

Abstract

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Year:  2009        PMID： 19626055      PMCID： PMC4094019          DOI： 10.1038/gt.2009.88

Source DB:  PubMed          Journal:  Gene Ther        ISSN： 0969-7128            Impact factor:   5.250


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  14 in total

1.  Environmental enrichment inhibits spontaneous apoptosis, prevents seizures and is neuroprotective.

Authors:  D Young; P A Lawlor; P Leone; M Dragunow; M J During
Journal:  Nat Med       Date:  1999-04       Impact factor: 53.440

Review 2.  Regulatable gene expression systems for gene therapy applications: progress and future challenges.

Authors:  S Goverdhana; M Puntel; W Xiong; J M Zirger; C Barcia; J F Curtin; E B Soffer; S Mondkar; G D King; J Hu; S A Sciascia; M Candolfi; D S Greengold; P R Lowenstein; M G Castro
Journal:  Mol Ther       Date:  2005-08       Impact factor: 11.454

3.  Obesity and diabetes in the developing world--a growing challenge.

Authors:  Parvez Hossain; Bisher Kawar; Meguid El Nahas
Journal:  N Engl J Med       Date:  2007-01-18       Impact factor: 91.245

4.  Brain-derived neurotrophic factor-deficient mice develop aggressiveness and hyperphagia in conjunction with brain serotonergic abnormalities.

Authors:  W E Lyons; L A Mamounas; G A Ricaurte; V Coppola; S W Reid; S H Bora; C Wihler; V E Koliatsos; L Tessarollo
Journal:  Proc Natl Acad Sci U S A       Date:  1999-12-21       Impact factor: 11.205

Review 5.  Therapeutic options for modifying cardiometabolic risk factors.

Authors:  Louis J Aronne
Journal:  Am J Med       Date:  2007-03       Impact factor: 4.965

6.  Molecular therapy of obesity and diabetes by a physiological autoregulatory approach.

Authors:  Lei Cao; En-Ju D Lin; Michael C Cahill; Chuansong Wang; Xianglan Liu; Matthew J During
Journal:  Nat Med       Date:  2009-03-08       Impact factor: 53.440

7.  Central LIF gene therapy suppresses food intake, body weight, serum leptin and insulin for extended periods.

Authors:  Elena Beretta; Harveen Dhillon; Pushpa S Kalra; Satya P Kalra
Journal:  Peptides       Date:  2002-05       Impact factor: 3.750

Review 8.  Promoters and serotypes: targeting of adeno-associated virus vectors for gene transfer in the rat central nervous system in vitro and in vivo.

Authors:  Z Shevtsova; J M I Malik; U Michel; M Bähr; S Kügler
Journal:  Exp Physiol       Date:  2004-11-12       Impact factor: 2.969

9.  Hyperphagia, severe obesity, impaired cognitive function, and hyperactivity associated with functional loss of one copy of the brain-derived neurotrophic factor (BDNF) gene.

Authors:  Juliette Gray; Giles S H Yeo; James J Cox; Jenny Morton; Anna-Lynne R Adlam; Julia M Keogh; Jack A Yanovski; Areeg El Gharbawy; Joan C Han; Y C Loraine Tung; John R Hodges; F Lucy Raymond; Stephen O'rahilly; I Sadaf Farooqi
Journal:  Diabetes       Date:  2006-12       Impact factor: 9.461

10.  Reducing hypothalamic AGRP by RNA interference increases metabolic rate and decreases body weight without influencing food intake.

Authors:  Hideo Makimura; Tooru M Mizuno; Jason W Mastaitis; Reuven Agami; Charles V Mobbs
Journal:  BMC Neurosci       Date:  2002-11-07       Impact factor: 3.288
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