Literature DB >> 19624416

Intrapulmonary and cutaneous siliconomas after silent silicone breast implant failure.

Adrian Dragu1, Dirk Theegarten, Alexander D Bach, Elias Polykandriotis, Andreas Arkudas, Ulrich Kneser, Raymund E Horch, Giulio Ingianni.   

Abstract

Since the implementation and use of silicone implants in breast surgery the risks are published and discussed. Especially, the incidence of late silicone implant rupture and its potential risk to induce local siliconomas are still under discussion and not sufficiently evaluated. So far literature data offer no information of intrapulmonal or peripheral located cutaneous siliconomas because of systemic migration of silicone after breast augmentation. In light of silicones checkered history, and given the large and growing number of women who choose to undergo breast augmentation surgery each year, the presented clinical findings in our study are likely to be of interest to medical professionals, producers, and consumers alike. We present six female patients with an average age of 55 (+/-5) years with bilateral rupture of silicone implants after breast augmentation for aesthetic reasons. The average time after operation was 18 (+/-6) years. In five patients, we identified peripheral located cutaneous siliconomas and one patient suffered from an intrapulmonal siliconoma. The diagnosis of bilateral rupture of the silicone implants was performed preoperatively by MRI-scans. All five peripheral cutaneous siliconomas and the intrapulmonal siliconoma were validated by histopathologic analysis. Six female patients suffered from bilateral rupture of silicone implants after breast augmentation. In five patients, we identified peripheral located cutaneous siliconomas which were surgically excised. One patient suffered from an intrapulmonal siliconoma. In this unique case a lobectomy with resection of the pulmonal segment 10 had to be performed. Clinical findings of peripheral cutaneous and even intrapulmonary siliconomas after bilateral rupture of silicone breast implants indicate a systemic hematogen or lymphatic pathway of silicone. These findings suggest that it is mandatory to inform the patient about the potential risk of local siliconomas, but also about the potential risk of peripheral cutaneous or even intrapulmonary siliconomas caused by systemic hematogen or lymphatic pathways of silicone after silent implant failure.

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Year:  2009        PMID: 19624416     DOI: 10.1111/j.1524-4741.2009.00765.x

Source DB:  PubMed          Journal:  Breast J        ISSN: 1075-122X            Impact factor:   2.431


  11 in total

1.  Silicon granuloma mimicking lung cancer.

Authors:  Liaquat Ali; Damian Mcgivern; Richard Teoh
Journal:  BMJ Case Rep       Date:  2012-07-19

Review 2.  A guide to breast implants for the non-breast specialist.

Authors:  Kate L Harvey; Sarah E Clark
Journal:  Womens Health (Lond)       Date:  2017-02-10

3.  Cytologic features of a pleural effusion after silicone breast implant rupture.

Authors:  José A Jiménez-Heffernan; Alejandra Rosell; Emma Vázquez-Espinosa; Carmen Idoate-Ortueta; Marta Solís-García; Eduardo Pacios
Journal:  Virchows Arch       Date:  2022-10-13       Impact factor: 4.535

4.  [Serious complications following gluteal injection of silicone].

Authors:  C Herink; P A Zwaka; M P Schön; M Mempel; C S Seitz
Journal:  Hautarzt       Date:  2013-08       Impact factor: 0.751

5.  A Case of Silicone and Sarcoid Granulomas in a Patient with "Highly Cohesive" Silicone Breast Implants: A Histopathologic and Laser Raman Microprobe Analysis.

Authors:  Todor I Todorov; Erik de Bakker; Diane Smith; Lisette C Langenberg; Linda A Murakata; Mark H H Kramer; Jose A Centeno; Prabath W B Nanayakkara
Journal:  Int J Environ Res Public Health       Date:  2021-04-24       Impact factor: 3.390

6.  Osteolysis and Cervical Cord Compression Secondary to Silicone Granuloma Formation around a Dorsal Spinal Cord Stimulator: A Case Report.

Authors:  John R Dimar; David T Endriga; Leah Y Carreon
Journal:  J Neurol Surg Rep       Date:  2016-06

7.  Skin deep: Cutaneous manifestation of PIP implant rupture.

Authors:  Máire-Caitlín Casey; Edward Jason Kelly
Journal:  JPRAS Open       Date:  2021-03-19

8.  Cutaneous silicone granuloma mimicking breast cancer after ruptured breast implant.

Authors:  Waseem Asim Ghulam El-Charnoubi; Trine Foged Henriksen; Jens Joergen Elberg
Journal:  Case Rep Dermatol Med       Date:  2012-01-26

9.  Silicone Migration after Buttock Augmentation.

Authors:  Rafael Biguria; Otto Rolando Ziegler
Journal:  Plast Reconstr Surg Glob Open       Date:  2017-12-28

10.  Silicone Migration and Late Hematoma following Silicone Implant Rupture: Case Report and Literature Review.

Authors:  Riley A Dean; Adam D Glener; Analise B Thomas; Steven R Glener; Silvia Kurtovic; Detlev Erdmann
Journal:  Plast Reconstr Surg Glob Open       Date:  2018-08-06
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