Association of lipid profile with ischemic stroke.

This study is an observational case control study conducted in the Neurology department of Dhaka Medical college Hospital (DMCH) to see the relation of ischemic stroke with different components of serum lipids. Cases and controls were selected following certain inclusion and exclusion criteria. Result showed that ischemic stroke was more common after the age of 50 years with mean age of 63.58+/-10.22 years. Male suffered more than female from ischemic stroke (M:F=2.57:1). 80% of the stroke patients belong to middle class economic condition who avail free services of Govt. hospitals. Hypertension and diabetes mellitus (DM) were found to be significant risk factors for ischemic stroke (P<0.01 and P<0.05 respectively). High level of serum total cholesterol and low density lipoprotein (LDL) cholesterol showed significant risk in ischemic stroke (p<0.05). In contrast, low level of high density lipoprotein (HDL) cholesterol appeared as a significant risk factor (p<0.01) indicating beneficial effect of HDL cholesterol on atherosclerotic process. Serum triglyceride level showed no significant effect on ischemic stroke (p>0.05).