| Literature DB >> 19622682 |
Patricia Ribeiro Porto1, Leticia Oliveira, Jair Mari, Eliane Volchan, Ivan Figueira, Paula Ventura.
Abstract
This systematic review aims to investigate neurobiological changes related to cognitive-behavioral therapy (CBT) in anxiety disorders detected through neuroimaging techniques and to identify predictors of response to treatment. Cognitive-behavioral therapy modified the neural circuits involved in the regulation of negative emotions and fear extinction in judged treatment responders. The only study on predictors of response to treatment was regarding obsessive-compulsive disorder and showed higher pretreatment regional metabolic activity in the left orbitofrontal cortex associated with a better response to behavioral therapy. Despite methodological limitations, neuroimaging studies revealed that CBT was able to change dysfunctions of the nervous system.Entities:
Mesh:
Year: 2009 PMID: 19622682 DOI: 10.1176/jnp.2009.21.2.114
Source DB: PubMed Journal: J Neuropsychiatry Clin Neurosci ISSN: 0895-0172 Impact factor: 2.198