Keiichiro Kume1. 1. Department of Gastroenterology and Metabolism, University of Occupational and Environmental Health Japan, School of Medicine, Kitakyusyu, Japan. k-kume@med.uoeh-u.ac.jp
Abstract
BACKGROUND/AIMS: In patients with early esophageal cancer post endoscopic mucosal resection (EMR), it is important to pay special attention to the metachronous, multiple esophageal cancers. The entire esophagus could be a source of new lesions including metachronous cancers. On the other hands, EMR is now a common treatment for esophageal cancer confined within the lamina propria mucosae, although this method is sometimes associated with local recurrences. We evaluated and compared metachronous cancers and local recurrences after EMR from the point of view of field cancerzation on the whole esophagus. METHODOLOGY: The clinical results following EMR for the treatment of m 1-2 esophageal cancer in 73 patients with 100 lesions were reviewed. RESULTS: The complete resection rate was 44.4%. Eight patients (11.0%) that endoscopically salvaged had the local recurrence. Two of these patients underwent complete en bloc resection. Metachronous cancers were observed in 16.4% of cases. CONCLUSIONS: EMR should be widely used in ml-2 esophageal cancer patients, since EMR (or coagulation) easy to perform could be a salvage treatment for recurrence and the incidence of metachronous cancer was clearly higher than that of the local recurrence.
BACKGROUND/AIMS: In patients with early esophageal cancer post endoscopic mucosal resection (EMR), it is important to pay special attention to the metachronous, multiple esophageal cancers. The entire esophagus could be a source of new lesions including metachronous cancers. On the other hands, EMR is now a common treatment for esophageal cancer confined within the lamina propria mucosae, although this method is sometimes associated with local recurrences. We evaluated and compared metachronous cancers and local recurrences after EMR from the point of view of field cancerzation on the whole esophagus. METHODOLOGY: The clinical results following EMR for the treatment of m 1-2 esophageal cancer in 73 patients with 100 lesions were reviewed. RESULTS: The complete resection rate was 44.4%. Eight patients (11.0%) that endoscopically salvaged had the local recurrence. Two of these patients underwent complete en bloc resection. Metachronous cancers were observed in 16.4% of cases. CONCLUSIONS: EMR should be widely used in ml-2 esophageal cancerpatients, since EMR (or coagulation) easy to perform could be a salvage treatment for recurrence and the incidence of metachronous cancer was clearly higher than that of the local recurrence.