BACKGROUND: To report three cases of early choroidal neovascularization (CNV) bridging after ranibizumab treatment. METHODS: Three patients with two separated foci of CNV secondary to age-related macular degeneration (ARMD), pathologic myopia and multifocal choroiditis were treated with monthly injections of ranibizumab por a period of 3 months. RESULTS: All three cases showed early coalescence across the fovea of the two neovascular foci, already 1 month after the first ranibizumab injection. Best-corrected visual acuity (BCVA) decreased in the three cases more than 20 letters due to early foveal involvement. CONCLUSIONS: Two different foci of CNV show a great tendency to decrease patients' vision because of neovascular bridging with foveal implication.
BACKGROUND: To report three cases of early choroidal neovascularization (CNV) bridging after ranibizumab treatment. METHODS: Three patients with two separated foci of CNV secondary to age-related macular degeneration (ARMD), pathologic myopia and multifocal choroiditis were treated with monthly injections of ranibizumab por a period of 3 months. RESULTS: All three cases showed early coalescence across the fovea of the two neovascular foci, already 1 month after the first ranibizumab injection. Best-corrected visual acuity (BCVA) decreased in the three cases more than 20 letters due to early foveal involvement. CONCLUSIONS: Two different foci of CNV show a great tendency to decrease patients' vision because of neovascular bridging with foveal implication.
Authors: David M Brown; Mark Michels; Peter K Kaiser; Jeffrey S Heier; Judy P Sy; Tsontcho Ianchulev Journal: Ophthalmology Date: 2009-01 Impact factor: 12.079