Pimwan Sookplung1, Monica S Vavilala. 1. Department of Anesthesiology, Harborview Injury Prevention and Research Center, University of Washington, Seattle, WA 98104, USA.
Abstract
PURPOSE OF REVIEW: Pediatric traumatic brain injury (TBI) is associated with significant morbidity and mortality. The purpose of this review is to discuss emerging concepts and to provide an update on the clinical evaluation, management, and predictors of outcome after pediatric TBI. RECENT FINDINGS: We review the epidemiology, patterns of injury, and pathophysiology of pediatric TBI and focus on selective 'hot topics' such as biomarkers, glucose control, and the potential benefits of hypothermia after pediatric TBI. SUMMARY: As TBI is the leading cause of death in children, research in this area is needed to advance our knowledge of the sequelae after and improve outcomes of children with TBI.
PURPOSE OF REVIEW: Pediatric traumatic brain injury (TBI) is associated with significant morbidity and mortality. The purpose of this review is to discuss emerging concepts and to provide an update on the clinical evaluation, management, and predictors of outcome after pediatric TBI. RECENT FINDINGS: We review the epidemiology, patterns of injury, and pathophysiology of pediatric TBI and focus on selective 'hot topics' such as biomarkers, glucose control, and the potential benefits of hypothermia after pediatric TBI. SUMMARY: As TBI is the leading cause of death in children, research in this area is needed to advance our knowledge of the sequelae after and improve outcomes of children with TBI.
Authors: Saeed Kayhanian; Adam M H Young; Ross L Ewen; Rory J Piper; Mathew R Guilfoyle; Joseph Donnelly; Helen M Fernandes; Matthew Garnett; Peter Smielewski; Marek Czosnyka; Shruti Agrawal; Peter J Hutchinson Journal: Sci Rep Date: 2019-03-05 Impact factor: 4.379