Literature DB >> 19620330

New variant of CTX-M-type extended-spectrum beta-lactamases, CTX-M-71, with a Gly238Cys substitution in a Klebsiella pneumoniae isolate from Bulgaria.

Ines Schneider1, Anne Marie Queenan, Rumyana Markovska, Boyka Markova, Emma Keuleyan, Adolf Bauernfeind.   

Abstract

A single Klebsiella pneumoniae strain isolated in a Bulgarian hospital was found to produce CTX-M-71, a new CTX-M variant characterized by one amino acid substitution from glycine to cysteine at position 238 in comparison to CTX-M-15. This exchange decreased the hydrolytic activity of the beta-lactamase for cefotaxime, ceftazidime, and cefepime.

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Year:  2009        PMID： 19620330      PMCID： PMC2764165          DOI： 10.1128/AAC.00461-09

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  18 in total

1.  A novel type of AmpC beta-lactamase, ACC-1, produced by a Klebsiella pneumoniae strain causing nosocomial pneumonia.

Authors:  A Bauernfeind; I Schneider; R Jungwirth; H Sahly; U Ullmann
Journal:  Antimicrob Agents Chemother       Date:  1999-08       Impact factor: 5.191

Review 2.  Growing group of extended-spectrum beta-lactamases: the CTX-M enzymes.

Authors:  R Bonnet
Journal:  Antimicrob Agents Chemother       Date:  2004-01       Impact factor: 5.191

3.  A standard numbering scheme for the class A beta-lactamases.

Authors:  R P Ambler; A F Coulson; J M Frère; J M Ghuysen; B Joris; M Forsman; R C Levesque; G Tiraby; S G Waley
Journal:  Biochem J       Date:  1991-05-15       Impact factor: 3.857

4.  A novel plasmid-mediated extended-spectrum beta-lactamase not derived from TEM- or SHV-type enzymes.

Authors:  H Bernard; C Tancrede; V Livrelli; A Morand; M Barthelemy; R Labia
Journal:  J Antimicrob Chemother       Date:  1992-05       Impact factor: 5.790

5.  Do CTX-M beta-lactamases hydrolyse ertapenem?

Authors:  Delphine Girlich; Laurent Poirel; Patrice Nordmann
Journal:  J Antimicrob Chemother       Date:  2008-07-28       Impact factor: 5.790

6.  An engineered disulfide bond between residues 69 and 238 in extended-spectrum beta-lactamase Toho-1 reduces its activity toward third-generation cephalosporins.

Authors:  Akiko Shimizu-Ibuka; Hiroshi Matsuzawa; Hiroshi Sakai
Journal:  Biochemistry       Date:  2004-12-21       Impact factor: 3.162

7.  The use of analytical isoelectric focusing for detection and identification of beta-lactamases.

Authors:  A Mathew; A M Harris; M J Marshall; G W Ross
Journal:  J Gen Microbiol       Date:  1975-05

8.  Novel plasmid-mediated beta-lactamase from Escherichia coli that inactivates oxyimino-cephalosporins.

Authors:  Y Matsumoto; F Ikeda; T Kamimura; Y Yokota; Y Mine
Journal:  Antimicrob Agents Chemother       Date:  1988-08       Impact factor: 5.191

9.  A new plasmidic cefotaximase in a clinical isolate of Escherichia coli.

Authors:  A Bauernfeind; H Grimm; S Schweighart
Journal:  Infection       Date:  1990 Sep-Oct       Impact factor: 3.553

10.  Extended-spectrum beta-lactamase (ESBL) CTX-M-15-producing Escherichia coli and Klebsiella pneumoniae in Sofia, Bulgaria.

Authors:  R Markovska; I Schneider; E Keuleyan; A Bauernfeind
Journal:  Clin Microbiol Infect       Date:  2004-08       Impact factor: 8.067
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  5 in total

1.  Trends in susceptibility of Escherichia coli from intra-abdominal infections to ertapenem and comparators in the United States according to data from the SMART program, 2009 to 2013.

Authors:  Sibylle H Lob; Krystyna M Kazmierczak; Robert E Badal; Meredith A Hackel; Samuel K Bouchillon; Douglas J Biedenbach; Daniel F Sahm
Journal:  Antimicrob Agents Chemother       Date:  2015-03-23       Impact factor: 5.191

2.  Interaction of CTX-M-15 enzyme with cefotaxime: a molecular modelling and docking study.

Authors:  Shazi Shakil; Asad Ullah Khan
Journal:  Bioinformation       Date:  2010-04-30

Review 3.  Epidemiology and genetics of CTX-M extended-spectrum β-lactamases in Gram-negative bacteria.

Authors:  Wei-Hua Zhao; Zhi-Qing Hu
Journal:  Crit Rev Microbiol       Date:  2012-06-15       Impact factor: 7.624

4.  Correlation between Identification of β-Lactamase Resistance Genes and Antimicrobial Susceptibility Profiles in Gram-Negative Bacteria: a Laboratory Data Analysis.

Authors:  Ammara Mushtaq; Rachel Chasan; Michael D Nowak; Meenakshi Rana; Sahrish Ilyas; Alberto E Paniz-Mondolfi; Emilia M Sordillo; Gopi Patel; Melissa R Gitman
Journal:  Microbiol Spectr       Date:  2022-03-07

5.  Infected foot ulcers in male and female diabetic patients: a clinico-bioinformative study.

Authors:  Shazi Shakil; Asad U Khan
Journal:  Ann Clin Microbiol Antimicrob       Date:  2010-01-14       Impact factor: 3.944
  5 in total

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