Circadian temperature variation and ageing.

In the present paper, an attempt is made to summarize current knowledge concerning the daily body temperature rhythm and its age-dependent alterations. Homeostatic and circadian control mechanisms are considered. Special attention is paid to the circadian system, as the mechanisms of autonomic control are the topic of another contribution to this special issue. Also, the interactions of the core body temperature rhythm with other circadian functions are discussed in detail as they constitute an essential part of the internal temporal order of living systems and thus guarantee their optimal functioning. In the second part of the paper, age-dependent changes in the circadian body temperature rhythm and their putative causes, considering circadian and homeostatic components, are described. Consequences for health and fitness and some possibilities to prevent adverse effect are mentioned in the final section. Copyright 2009 Elsevier Ireland Ltd. All rights reserved.