Literature DB >> 19619577

Preparedness for an anthrax attack.

David R Franz1.   

Abstract

Bacillus anthracis is a long-known bacterial organism with a uniquely stable spore stage. Its stability and the lethal disease which results when the spore is inhaled made it a favorite of state-sponsored biological weapons programs throughout the Cold War era. It is also believed to be high on the list of candidate microbial agents which could be used by terrorist groups or lone actors. Its unique characteristics make protection of humans, especially civilians, from an intentional biological attack very difficult. The author argues that an all-hazards/public health approach - which would also be needed for any natural or deliberate outbreak, no matter the agent - should serve as a foundation of preparation for the specific anthrax countermeasures. Because B. anthracis is a unique organism, specific countermeasures for anthrax detection, diagnostics, prophylaxis and therapy, should be developed in nations or regions where the threat of biological attack is believed to warrant such preparation. Other considerations for a nation interested in anthrax preparedness are discussed.

Entities:  

Mesh:

Year:  2009        PMID: 19619577     DOI: 10.1016/j.mam.2009.07.002

Source DB:  PubMed          Journal:  Mol Aspects Med        ISSN: 0098-2997


  10 in total

1.  A Learner-led, Discussion-based Elective on Emerging Infectious Disease.

Authors:  Clinton Mathias
Journal:  Am J Pharm Educ       Date:  2015-08-25       Impact factor: 2.047

2.  Comprehensive Laboratory Evaluation of a Highly Specific Lateral Flow Assay for the Presumptive Identification of Bacillus anthracis Spores in Suspicious White Powders and Environmental Samples.

Authors:  Jason G Ramage; Kristin W Prentice; Lindsay DePalma; Kodumudi S Venkateswaran; Sruti Chivukula; Carol Chapman; Melissa Bell; Shomik Datta; Ajay Singh; Alex Hoffmaster; Jawad Sarwar; Nishanth Parameswaran; Mrinmayi Joshi; Nagarajan Thirunavkkarasu; Viswanathan Krishnan; Stephen Morse; Julie R Avila; Shashi Sharma; Peter L Estacio; Larry Stanker; David R Hodge; Segaran P Pillai
Journal:  Health Secur       Date:  2016 Sep-Oct

3.  Pediatric anthrax clinical management.

Authors:  John S Bradley; Georgina Peacock; Steven E Krug; William A Bower; Amanda C Cohn; Dana Meaney-Delman; Andrew T Pavia
Journal:  Pediatrics       Date:  2014-05       Impact factor: 7.124

4.  Deterministic models of inhalational anthrax in New Zealand white rabbits.

Authors:  Bradford Gutting
Journal:  Biosecur Bioterror       Date:  2014-02-14

5.  Targeted silencing of anthrax toxin receptors protects against anthrax toxins.

Authors:  Maria T Arévalo; Ashley Navarro; Chenoa D Arico; Junwei Li; Omar Alkhatib; Shan Chen; Diana Diaz-Arévalo; Mingtao Zeng
Journal:  J Biol Chem       Date:  2014-04-17       Impact factor: 5.157

6.  Anthrax lethal toxin disrupts intestinal barrier function and causes systemic infections with enteric bacteria.

Authors:  Chen Sun; Hui Fang; Tao Xie; Roger D Auth; Nayana Patel; Patrick R Murray; Philip J Snoy; David M Frucht
Journal:  PLoS One       Date:  2012-03-16       Impact factor: 3.240

7.  Genetic characterization of Bacillus anthracis in Guizhou Province, Southwest of China.

Authors:  Shijun Li; Qing Ma; Hong Chen; Dingming Wang; Ying Liu; Xiaoyu Wei; Lv You; Guanghai Yao; Kecheng Tian; Guangpeng Tang
Journal:  BMC Microbiol       Date:  2015-03-31       Impact factor: 3.605

8.  A single-dose PLGA encapsulated protective antigen domain 4 nanoformulation protects mice against Bacillus anthracis spore challenge.

Authors:  Manish Manish; Amit Rahi; Manpreet Kaur; Rakesh Bhatnagar; Samer Singh
Journal:  PLoS One       Date:  2013-04-29       Impact factor: 3.240

9.  Evidence-based support for the all-hazards approach to emergency preparedness.

Authors:  Bruria Adini; Avishay Goldberg; Robert Cohen; Daniel Laor; Yaron Bar-Dayan
Journal:  Isr J Health Policy Res       Date:  2012-10-25

10.  Sensitive and Specific Recombinase Polymerase Amplification Assays for Fast Screening, Detection, and Identification of Bacillus anthracis in a Field Setting.

Authors:  Mostafa Bentahir; Jérôme Ambroise; Cathy Delcorps; Paola Pilo; Jean-Luc Gala
Journal:  Appl Environ Microbiol       Date:  2018-05-17       Impact factor: 4.792

  10 in total

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