| Literature DB >> 19618273 |
Julio Villatoro-Hernandez1, Alma Yolanda Arce-Mendoza, Adrian G Rosas-Taraco, Sandra Cecilia Esparza-González, Santos Guzmán-López, Rodrigo E Elizondo-Omaña, Arturo Chávez-Reyes, Odila Saucedo-Cárdenas, Roberto Montes de Oca Luna.
Abstract
Chemokines are members of the super family of cytokines necessary for leukocyte recruitment in tissues and lymphoid organs. The interferon-gamma inducible protein-10 (IP-10) chemo-attracts CXCR3-expressing cells, such as activated T lymphocytes and monocytes. We have genetically engineered a strain of Lactococcus lactis to secrete a biologically active murine IP-10 that interacts with human CXCR3, its homolog receptor, and chemo-attracts human CD3+ T lymphocytes.Entities:
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Year: 2009 PMID： 19618273 DOI： 10.1007/s10529-009-0081-7
Source DB: PubMed Journal: Biotechnol Lett ISSN： 0141-5492 Impact factor: 2.461