Literature DB >> 196172

Forces and structural limitations of binding of thyrotrophin-releasing factor to the thyrotrophin-releasing receptor: the pyroglutamic acid moiety.

H J Goren, L G Bauce, W Vale.   

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Year:  1977        PMID: 196172

Source DB:  PubMed          Journal:  Mol Pharmacol        ISSN: 0026-895X            Impact factor:   4.436


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  7 in total

1.  Structures of human Golgi-resident glutaminyl cyclase and its complexes with inhibitors reveal a large loop movement upon inhibitor binding.

Authors:  Kai-Fa Huang; Su-Sen Liaw; Wei-Lin Huang; Cho-Yun Chia; Yan-Chung Lo; Yi-Ling Chen; Andrew H-J Wang
Journal:  J Biol Chem       Date:  2011-02-01       Impact factor: 5.157

2.  Glutaminyl cyclase knock-out mice exhibit slight hypothyroidism but no hypogonadism: implications for enzyme function and drug development.

Authors:  Stephan Schilling; Stephanie Kohlmann; Christoph Bäuscher; Reinhard Sedlmeier; Birgit Koch; Rico Eichentopf; Andreas Becker; Holger Cynis; Torsten Hoffmann; Sabine Berg; Ernst-Joachim Freyse; Stephan von Hörsten; Steffen Rossner; Sigrid Graubner; Hans-Ulrich Demuth
Journal:  J Biol Chem       Date:  2011-02-17       Impact factor: 5.157

Review 3.  Pyroglutamic acid. Non-metabolic formation, function in proteins and peptides, and characteristics of the enzymes effecting its removal.

Authors:  G N Abraham; D N Podell
Journal:  Mol Cell Biochem       Date:  1981-08-11       Impact factor: 3.396

4.  Native pyroglutamation of huwentoxin-IV: a post-translational modification that increases the trapping ability to the sodium channel.

Authors:  Mingqiang Rong; Zhigui Duan; Juliang Chen; Jianglin Li; Yuchen Xiao; Songping Liang
Journal:  PLoS One       Date:  2013-06-24       Impact factor: 3.240

5.  N-terminal pyroglutamate formation in CX3CL1 is essential for its full biologic activity.

Authors:  Astrid Kehlen; Monique Haegele; Livia Böhme; Holger Cynis; Torsten Hoffmann; Hans-Ulrich Demuth
Journal:  Biosci Rep       Date:  2017-08-23       Impact factor: 3.840

Review 6.  The Structural Basis of Peptide Binding at Class A G Protein-Coupled Receptors.

Authors:  Oanh Vu; Brian Joseph Bender; Lisa Pankewitz; Daniel Huster; Annette G Beck-Sickinger; Jens Meiler
Journal:  Molecules       Date:  2021-12-30       Impact factor: 4.411

7.  Linked production of pyroglutamate-modified proteins via self-cleavage of fusion tags with TEV protease and autonomous N-terminal cyclization with glutaminyl cyclase in vivo.

Authors:  Yan-Ping Shih; Chi-Chi Chou; Yi-Ling Chen; Kai-Fa Huang; Andrew H-J Wang
Journal:  PLoS One       Date:  2014-04-14       Impact factor: 3.240

  7 in total

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