[Cutaneous side effects of antiretroviral drugs].

The goal of our study was to report cutaneous side effects of anti retroviral drugs. For this purpose we performed a transversal prospective trial during 6 month in the dermatological department and in the out patients management department of Dakar. Heighty four (84) cutaneous side effects were encounted in 38 HIV infected patients. There were 6,1% of toxidermies, severe in 3 cases (2 Stevens Johnson syndrome d 1 DRESS), 3,5% of immunitary restauration syndrome (2 zonas, 4 herpes) and 3,9% of lipodystrophy. The putative drugs of toxidermies were Nevirapine, Effavirenz and Zidovudine and antiproteases and Stavudine were the cause of lipodystrophy. The duration before apparitions of the lesions was 16,9 days for toxidermies, 45,5% for immunitary restauration syndrome and 40,72 months for the lipodystrophy.