Literature DB >> 19616195

Cognitive behavioral therapy versus paroxetine in the treatment of hypochondriasis: an 18-month naturalistic follow-up.

Anja Greeven1, Anton J L M van Balkom, Rien van der Leeden, Jille W Merkelbach, Odile A van den Heuvel, Philip Spinhoven.   

Abstract

BACKGROUND: The present maintenance study investigated whether the reduction in hypochondriacal complaints after initial treatment with CBT or paroxetine sustained during a follow-up period and whether psychiatric severity at pretest predicted the course of hypochondriacal symptoms.
METHOD: A naturalistic follow-up period of 18 months after a 16-week RCT consisting of 33 patients initially allocated to a CBT condition and 29 patients to a paroxetine condition. The main outcome measure was the Whiteley Index.
RESULTS: The initial treatment effect of CBT and paroxetine sustained during the follow-up period. No significant differences between CBT and paroxetine were found. Treatment course could not be predicted by psychiatric comorbidity.
CONCLUSION: CBT and paroxetine are both effective treatments for hypochondriasis in the long term.

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Year:  2009        PMID: 19616195     DOI: 10.1016/j.jbtep.2009.06.005

Source DB:  PubMed          Journal:  J Behav Ther Exp Psychiatry        ISSN: 0005-7916


  7 in total

1.  Paroxetine up-regulates neurogenesis in hippocampus-derived neural stem cell from fetal rats.

Authors:  Zheng-Wu Peng; Fen Xue; Hua-Ning Wang; Rui-Guo Zhang; Yun-Chun Chen; Ying Wang; Li-Yi Zhang; Juan Fan; Qing-Rong Tan
Journal:  Mol Cell Biochem       Date:  2013-01-05       Impact factor: 3.396

2.  [Psychopharmacological treatment in patients with somatoform disorders and functional body syndromes].

Authors:  H P Kapfhammer
Journal:  Nervenarzt       Date:  2012-09       Impact factor: 1.214

Review 3.  Managing Problematic Usage of the Internet and Related Disorders in an Era of Diagnostic Transition: An Updated Review.

Authors:  Bernardo Dell'Osso; Ilaria Di Bernardo; Matteo Vismara; Eleonora Piccoli; Federica Giorgetti; Laura Molteni; Naomi A Fineberg; Calogero Virzì; Henrietta Bowden-Jones; Roberto Truzoli; Caterina Viganò
Journal:  Clin Pract Epidemiol Ment Health       Date:  2021-07-14

4.  Rosmarinic acid ameliorates depressive-like behaviors in a rat model of CUS and Up-regulates BDNF levels in the hippocampus and hippocampal-derived astrocytes.

Authors:  Xiang Jin; Peng Liu; Fengchi Yang; Ya-Hong Zhang; Danmin Miao
Journal:  Neurochem Res       Date:  2013-06-12       Impact factor: 3.996

Review 5.  Recent Advances in the Understanding and Treatment of Health Anxiety.

Authors:  Peter Tyrer
Journal:  Curr Psychiatry Rep       Date:  2018-06-22       Impact factor: 5.285

6.  Long-term effect of cognitive-behavioural therapy in patients with Hypochondriacal Disorder.

Authors:  Kari-Elise Frøystad Veddegjærde; Børge Sivertsen; Jens Christoffer Skogen; Otto Robert Frans Smith; Ingvard Wilhelmsen
Journal:  BJPsych Open       Date:  2020-04-29

7.  Predicting the outcome of a cognitive-behavioral group training for patients with unexplained physical symptoms: a one-year follow-up study.

Authors:  Lyonne N L Zonneveld; Yanda R van Rood; Cornelis G Kooiman; Reinier Timman; Adriaan van 't Spijker; Jan J V Busschbach
Journal:  BMC Public Health       Date:  2012-10-08       Impact factor: 3.295

  7 in total

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