Literature DB >> 1961248

Minisatellite repeat coding as a digital approach to DNA typing.

A J Jeffreys1, A MacLeod, K Tamaki, D L Neil, D G Monckton.   

Abstract

Most DNA typing systems used in forensic and legal medicine assay allelic length variation at tandem repetitive DNA regions such as minisatellites. A simple alternative approach that displays patterns of variant repeat units along minisatellite alleles is described here. This produces DNA profiles as extraordinarily variable digital sequences appropriate for forensic investigations, including computer databasing, and for analysing allele diversity and the role of recombination in minisatellite instability.

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Year:  1991        PMID: 1961248     DOI: 10.1038/354204a0

Source DB:  PubMed          Journal:  Nature        ISSN: 0028-0836            Impact factor:   49.962


  96 in total

1.  Meiotic recombination and flanking marker exchange at the highly unstable human minisatellite CEB1 (D2S90).

Authors:  J Buard; A C Shone; A J Jeffreys
Journal:  Am J Hum Genet       Date:  2000-06-26       Impact factor: 11.025

2.  High-throughput SNP allele-frequency determination in pooled DNA samples by kinetic PCR.

Authors:  S Germer; M J Holland; R Higuchi
Journal:  Genome Res       Date:  2000-02       Impact factor: 9.043

3.  Minisatellite marker analysis of Trypanosoma brucei: reconciliation of clonal, panmictic, and epidemic population genetic structures.

Authors:  A MacLeod; A Tweedie; S C Welburn; I Maudlin; C M Turner; A Tait
Journal:  Proc Natl Acad Sci U S A       Date:  2000-11-21       Impact factor: 11.205

4.  Evolutionary fate of an unstable human minisatellite deduced from sperm-mutation spectra of individual alleles.

Authors:  Jérôme Buard; Charles Brenner; Alec J Jeffreys
Journal:  Am J Hum Genet       Date:  2002-02-21       Impact factor: 11.025

5.  Quantitative detection of single nucleotide polymorphisms for a pooled sample by a bioluminometric assay coupled with modified primer extension reactions (BAMPER).

Authors:  G Zhou; M Kamahori; K Okano; G Chuan; K Harada; H Kambara
Journal:  Nucleic Acids Res       Date:  2001-10-01       Impact factor: 16.971

6.  Structural analysis of insulin minisatellite alleles reveals unusually large differences in diversity between Africans and non-Africans.

Authors:  John D H Stead; Alec J Jeffreys
Journal:  Am J Hum Genet       Date:  2002-10-28       Impact factor: 11.025

7.  Sp1 binds to the precise locus of end processing within the terminal repeats of Epstein-Barr virus DNA.

Authors:  R Sun; T A Spain; S F Lin; G Miller
Journal:  J Virol       Date:  1997-08       Impact factor: 5.103

8.  Global haplotype diversity in the human insulin gene region.

Authors:  John D H Stead; Matthew E Hurles; Alec J Jeffreys
Journal:  Genome Res       Date:  2003-09       Impact factor: 9.043

9.  DNA fingerprinting--a valuable new technique for the characterisation of cell lines.

Authors:  G Stacey; B Bolton; A Doyle; B Griffiths
Journal:  Cytotechnology       Date:  1992       Impact factor: 2.058

10.  Allelic associations of two polymorphic microsatellites in intron 40 of the human von Willebrand factor gene.

Authors:  S D Pena; K T de Souza; M de Andrade; R Chakraborty
Journal:  Proc Natl Acad Sci U S A       Date:  1994-01-18       Impact factor: 11.205

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