OBJECTIVE: Allergic rhinitis can determine the presence and type of asthma. The main aim of this study was to evaluate the link between allergic rhinitis, asthma, and skin test sensitization in patients with allergic rhinitis. METHODS: Patients with allergic rhinitis, aged 10 to 50 years, were consecutively enrolled at different allergy centers in Spain and Portugal. All the patients underwent skin prick tests with a panel of 20 biologically standardized aeroallergens. Allergic rhinitis was classified according to etiology and the Allergic Rhinitis and its Impact on Asthma guidelines and asthma was classified according to the Global Initiative for Asthma guidelines. RESULTS: A total of 3225 patients, with a mean age of 27 years, were evaluated. House dust mites and grass and olive tree pollens were the most common aeroallergens. The mean (SD) number of positive skin tests per patient was 6.5 (4), the mean wheal size was 42.3 (28) mm2, and the mean atopy index was 6.5 (2). Forty-nine percent of the patients had concomitant asthma. Asthma severity was associated with a longer time since onset (P < .04) and allergic rhinitis severity (P < .001). Patients with concomitant asthma had a significantly higher number of aeroallergens and sensitization intensity than those without asthma (P < .001). CONCLUSIONS: In this broad population sample, the presence and type of asthma was influenced by skin sensitization and both time since onset and severity of allergic rhinitis.
OBJECTIVE:Allergic rhinitis can determine the presence and type of asthma. The main aim of this study was to evaluate the link between allergic rhinitis, asthma, and skin test sensitization in patients with allergic rhinitis. METHODS:Patients with allergic rhinitis, aged 10 to 50 years, were consecutively enrolled at different allergy centers in Spain and Portugal. All the patients underwent skin prick tests with a panel of 20 biologically standardized aeroallergens. Allergic rhinitis was classified according to etiology and the Allergic Rhinitis and its Impact on Asthma guidelines and asthma was classified according to the Global Initiative for Asthma guidelines. RESULTS: A total of 3225 patients, with a mean age of 27 years, were evaluated. House dust mites and grass and olive tree pollens were the most common aeroallergens. The mean (SD) number of positive skin tests per patient was 6.5 (4), the mean wheal size was 42.3 (28) mm2, and the mean atopy index was 6.5 (2). Forty-nine percent of the patients had concomitant asthma. Asthma severity was associated with a longer time since onset (P < .04) and allergic rhinitis severity (P < .001). Patients with concomitant asthma had a significantly higher number of aeroallergens and sensitization intensity than those without asthma (P < .001). CONCLUSIONS: In this broad population sample, the presence and type of asthma was influenced by skin sensitization and both time since onset and severity of allergic rhinitis.
Authors: Agnieszka Lipiec; Adam Sybilski; Jarosław Komorowski; Konrad Furmańczyk; Andrzej Namysłowski; Wojciech Zieliński; Filip Raciborski; Artur Z Białoszewski; Bolesław Samoliński Journal: Postepy Dermatol Alergol Date: 2019-04-09 Impact factor: 1.837
Authors: Giorgio Ciprandi; Davide Caimmi; Michele Miraglia Del Giudice; Mario La Rosa; Carmelo Salpietro; Gian Luigi Marseglia Journal: Allergy Asthma Immunol Res Date: 2012-02-08 Impact factor: 5.764
Authors: C Cingi; P Gevaert; R Mösges; C Rondon; V Hox; M Rudenko; N B Muluk; G Scadding; F Manole; C Hupin; W J Fokkens; C Akdis; C Bachert; P Demoly; J Mullol; A Muraro; N Papadopoulos; R Pawankar; P Rombaux; E Toskala; L Kalogjera; E Prokopakis; P W Hellings; J Bousquet Journal: Clin Transl Allergy Date: 2017-06-01 Impact factor: 5.871
Authors: Diana L Silva; Susana de Barayazarra; Antonio Valero; Elizabeth Garcia; Silvia Uriarte; Augusto Peñaranda; Edgardo Chapman; Maria B Garcia; Jaime Ocampo; Viviana Valencia; Sergio Moreno; Silvana Corelli; Belkis Lopez; Luis F Ramírez; Lucía Cecilia Pérez; Edgardo Jares; Carlos D Serrano Journal: Front Allergy Date: 2022-08-24