Literature DB >> 19609772

[Abdominal aortic aneurysm].

N Diehm1.   

Abstract

Abdominal aortic aneurysms (AAA) confer a substantial healthcare burden in the Western world. Surgical or endovascular therapy is indicated in patients with a maximum diameter exceeding 5.5 cm. Patients with smaller AAA must undergo a specific ultrasound surveillance program aimed at avoiding exposure to an increased risk of rupture once their AAA exceeds the threshold for active treatment. Based on improved understanding of the pathophysiology of AAA, recent years provided initial insight into potential medical treatment options. The presence of AAA is currently regarded a coronary artery disease risk equivalent. ACE inhibitors, statins and JNK-inhibitors were shown to have the potential to slow down progression. Since cigarette smoking is the main risk factor for both the development and progression of AAA, smoking cessation remains a key goal. Further prospective studies will assess the clinical efficacy of various promising drug treatment approaches aimed at slowing disease progression of small AAA and after endovascular therapy.

Entities:  

Mesh:

Year:  2009        PMID: 19609772     DOI: 10.1007/s00108-009-2362-6

Source DB:  PubMed          Journal:  Internist (Berl)        ISSN: 0020-9554            Impact factor:   0.743


  22 in total

1.  Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III).

Authors: 
Journal:  JAMA       Date:  2001-05-16       Impact factor: 56.272

2.  Appraisal era for endovascular repair of abdominal aortic aneurysms.

Authors:  F Dick; L C Brown; J T Powell; J Reise; R M Greenhalgh
Journal:  Acta Chir Belg       Date:  2008 May-Jun       Impact factor: 1.090

Review 3.  Current evidence and prospects for medical treatment of abdominal aortic aneurysms.

Authors:  N Diehm; J Schmidli; D Dai-Do; I Baumgartner
Journal:  Vasa       Date:  2005-11       Impact factor: 1.961

4.  The aneurysm detection and management study screening program: validation cohort and final results. Aneurysm Detection and Management Veterans Affairs Cooperative Study Investigators.

Authors:  F A Lederle; G R Johnson; S E Wilson; E P Chute; R J Hye; M S Makaroun; G W Barone; D Bandyk; G L Moneta; R G Makhoul
Journal:  Arch Intern Med       Date:  2000-05-22

5.  Angiotensin-converting enzyme inhibitors and aortic rupture: a population-based case-control study.

Authors:  Daniel G Hackam; Deva Thiruchelvam; Donald A Redelmeier
Journal:  Lancet       Date:  2006-08-19       Impact factor: 79.321

Review 6.  Management of popliteal artery aneurysms.

Authors:  Maher Hamish; Alistair Lockwood; Christine Cosgrove; Alasdair J Walker; Denis Wilkins; Simon Ashley
Journal:  ANZ J Surg       Date:  2006-10       Impact factor: 1.872

7.  A combination of statins and beta-blockers is independently associated with a reduction in the incidence of perioperative mortality and nonfatal myocardial infarction in patients undergoing abdominal aortic aneurysm surgery.

Authors:  M D Kertai; E Boersma; C M Westerhout; J Klein; H Van Urk; J J Bax; J R T C Roelandt; D Poldermans
Journal:  Eur J Vasc Endovasc Surg       Date:  2004-10       Impact factor: 7.069

8.  Patients with abdominal aortic aneurysm: are we missing the opportunity for cardiovascular risk reduction?

Authors:  G M Lloyd; J D Newton; M G A Norwood; S C Franks; M J Bown; R D Sayers
Journal:  J Vasc Surg       Date:  2004-10       Impact factor: 4.268

9.  Mortality results for randomised controlled trial of early elective surgery or ultrasonographic surveillance for small abdominal aortic aneurysms. The UK Small Aneurysm Trial Participants.

Authors: 
Journal:  Lancet       Date:  1998-11-21       Impact factor: 79.321

10.  Abdominal aortic aneurysm expansion: risk factors and time intervals for surveillance.

Authors:  Anthony R Brady; Simon G Thompson; F Gerald R Fowkes; Roger M Greenhalgh; Janet T Powell
Journal:  Circulation       Date:  2004-06-21       Impact factor: 29.690

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