Literature DB >> 19609421

Clinical outcomes after percutaneous vertebroplasty for pathologic compression fractures in osteolytic metastatic spinal disease.

Bong-Suk Lim1, Ung-Kyu Chang, Sang-Min Youn.   

Abstract

OBJECTIVE: Percutaneous vertebroplasty (VP) can provide immediate stabilization in pathologic fractures of spinal tumors. However, long term follow-up data in cases of pathologic fractures are lacking. The authors report follow-up results of VP in 185 pathologic fractures of 102 spinal tumor patients.
METHODS: Percutaneous VP was performed at 185 vertebral bodies of 102 patients from 2001 to 2007. Retrospective analysis was done with medical records and radiological data. The change of visual analogue score (VAS), vertebral body (VB) height and kyphotic angle were measured preoperatively and on postoperative one day and at 3, 6, and 12 months.
RESULTS: The patients were composed of metastatic spine tumors (81%) and multiple myeloma (19%). Involved spinal segments were between T6 and L5. Mean follow-up period was 12.2 months. VAS for back pain was 8.24 preoperatively, 3.59 (postoperative one day), 4.08 (three months) and 5.22 (one year). VB compression ratio changed from 21.33% preoperatively to 13.82% (postoperative one day), 14.36% (three month), and 16.04% (one year). Kyphotic angle changed from 15.35 degrees preoperatively to 12.03 degrees (postoperative one day), 13.64 degrees (three month), and 15.61 degrees (one year).
CONCLUSION: Immediate pain relief was definite after VP in pathologic compression fracture of osteolytic spinal disease. Although VAS was slightly increased on one year follow-up, VP effect was maintained without significant change. These results indicate that VP could be a safe and effective procedure as a palliative treatment of the spinal tumor patients.

Entities:  

Keywords:  Multiple myeloma; Percutaneous vertebroplasty; Spinal metastasis; Vertebral compression fractures

Year:  2009        PMID: 19609421      PMCID: PMC2711235          DOI: 10.3340/jkns.2009.45.6.369

Source DB:  PubMed          Journal:  J Korean Neurosurg Soc        ISSN: 1225-8245


  19 in total

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Authors:  J G Pilitsis; S S Rengachary
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2.  Percutaneous vertebroplasty with polymethylmethacrylate. Technique, indications, and results.

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Review 3.  Malignant bone pain: pathophysiology and treatment.

Authors:  S Mercadante
Journal:  Pain       Date:  1997-01       Impact factor: 6.961

4.  Percutaneous polymethylmethacrylate vertebroplasty in the treatment of osteoporotic vertebral body compression fractures: technical aspects.

Authors:  M E Jensen; A J Evans; J M Mathis; D F Kallmes; H J Cloft; J E Dion
Journal:  AJNR Am J Neuroradiol       Date:  1997 Nov-Dec       Impact factor: 3.825

5.  Percutaneous vertebroplasty in patients with osteolytic metastases or multiple myeloma.

Authors:  B Cortet; A Cotten; N Boutry; F Dewatre; R M Flipo; B Duquesnoy; P Chastanet; B Delcambre
Journal:  Rev Rhum Engl Ed       Date:  1997-03

6.  Percutaneous vertebroplasty in the treatment of osteoporotic vertebral compression fractures: an open prospective study.

Authors:  B Cortet; A Cotten; N Boutry; R M Flipo; B Duquesnoy; P Chastanet; B Delcambre
Journal:  J Rheumatol       Date:  1999-10       Impact factor: 4.666

7.  Balloon kyphoplasty for the treatment of pathological vertebral compressive fractures.

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Review 8.  Radiation for bone metastases: conventional techniques and the role of systemic radiopharmaceuticals.

Authors:  N A Janjan
Journal:  Cancer       Date:  1997-10-15       Impact factor: 6.860

9.  Percutaneous vertebroplasty and kyphoplasty for painful vertebral body fractures in cancer patients.

Authors:  Daryl R Fourney; Donald F Schomer; Remi Nader; Jennifer Chlan-Fourney; Dima Suki; Kamran Ahrar; Laurence D Rhines; Ziya L Gokaslan
Journal:  J Neurosurg       Date:  2003-01       Impact factor: 5.115

Review 10.  Management of painful bone metastases.

Authors:  Sebastiano Mercadante; Fabio Fulfaro
Journal:  Curr Opin Oncol       Date:  2007-07       Impact factor: 3.645

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  9 in total

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Authors:  Flavio Tancioni; Martin Lorenzetti; Pierina Navarria; Andrea Nozza; Luca Castagna; Paolo Gaetani; Enrico Aimar; Daniel Levi; Antonio Di Ieva; Patrizia Pisano; Armando Santoro; Marta Scorsetti; Riccardo Rodriguez y Baena
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Review 2.  Vertebral augmentation in patients with multiple myeloma: a pooled analysis of published case series.

Authors:  O A Khan; W Brinjikji; D F Kallmes
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Review 3.  Vertebral Augmentation Involving Vertebroplasty or Kyphoplasty for Cancer-Related Vertebral Compression Fractures: A Systematic Review.

Authors: 
Journal:  Ont Health Technol Assess Ser       Date:  2016-05-01

4.  Continuous multiple vertebral compression fractures in multiple myeloma patient.

Authors:  Sang Moon Hong; Tae Wan Kim; Kwan Ho Park
Journal:  Korean J Spine       Date:  2012-03-31

5.  Clinical efficacy of percutaneous vertebroplasty combined with intensity-modulated radiotherapy for spinal metastases in patients with NSCLC.

Authors:  Yi Li; Yi Qing; Zhimin Zhang; Mengxia Li; Jiaying Xie; Ge Wang; Dong Wang
Journal:  Onco Targets Ther       Date:  2015-08-19       Impact factor: 4.147

6.  Multiple Myeloma and Epidural Spinal Cord Compression : Case Presentation and a Spine Surgeon's Perspective.

Authors:  Kee-Yong Ha; Young-Hoon Kim; Hyun-Woo Kim
Journal:  J Korean Neurosurg Soc       Date:  2013-08-31

7.  Circulating Tumour Cell Release after Cement Augmentation of Vertebral Metastases.

Authors:  Malte Mohme; Sabine Riethdorf; Marc Dreimann; Stefan Werner; Cecile L Maire; Simon A Joosse; Frederic Bludau; Volkmar Mueller; Rui P L Neves; Nikolas H Stoecklein; Katrin Lamszus; Manfred Westphal; Klaus Pantel; Harriet Wikman; Sven O Eicker
Journal:  Sci Rep       Date:  2017-08-03       Impact factor: 4.379

8.  Patterns of Treatment for Metastatic Pathological Fractures of the Spine: The Efficacy of Each Treatment Modality.

Authors:  Jae Hwan Cho; Jung-Ki Ha; Chang Ju Hwang; Dong-Ho Lee; Choon Sung Lee
Journal:  Clin Orthop Surg       Date:  2015-11-13

Review 9.  A review and update of vertebral fractures due to metastatic tumors of various sites to the spine: Percutaneous vertebroplasty.

Authors:  Mohamad Mansoorinasab; Hesam Abdolhoseinpour
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  9 in total

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