OBJECTIVE: To compare blood pressure (BP) in adolescence (11-12 years) among the offspring of preeclamptic and normotensive pregnancies. METHOD: SBP and DBP of 181 girls and boys born after pregnancies with preeclampsia were measured and compared with the BP of 356 age-matched girls and boys of normotensive pregnancies. The association of preeclampsia with later BP was adjusted for perinatal information, anthropometric factors at follow-up, and maternal BP and BMI. RESULTS: In the preeclampsia group, SBP in early adolescence was higher than in the normotensive group (115.3 vs. 113.5 mmHg, P = 0.03), but there was no difference in DBP (66.4 vs. 65.3 mmHg, P = 0.10). After adjustment for maternal body mass and BP, the difference in SBP was largely attenuated. CONCLUSION: The higher SBP among adolescent offspring of preeclamptic pregnancies could be mediated by maternal body mass or BP, factors that are positively associated with the risk of preeclampsia in pregnancy.
OBJECTIVE: To compare blood pressure (BP) in adolescence (11-12 years) among the offspring of preeclamptic and normotensive pregnancies. METHOD:SBP and DBP of 181 girls and boys born after pregnancies with preeclampsia were measured and compared with the BP of 356 age-matched girls and boys of normotensive pregnancies. The association of preeclampsia with later BP was adjusted for perinatal information, anthropometric factors at follow-up, and maternal BP and BMI. RESULTS: In the preeclampsia group, SBP in early adolescence was higher than in the normotensive group (115.3 vs. 113.5 mmHg, P = 0.03), but there was no difference in DBP (66.4 vs. 65.3 mmHg, P = 0.10). After adjustment for maternal body mass and BP, the difference in SBP was largely attenuated. CONCLUSION: The higher SBP among adolescent offspring of preeclamptic pregnancies could be mediated by maternal body mass or BP, factors that are positively associated with the risk of preeclampsia in pregnancy.
Authors: Rocio Muñoz-Hernandez; Maria L Miranda; Pablo Stiefel; Ruei-Zeng Lin; Juan M Praena-Fernández; Maria J Dominguez-Simeon; Jose Villar; Rafael Moreno-Luna; Juan M Melero-Martin Journal: Hypertension Date: 2014-04-21 Impact factor: 10.190
Authors: Elizabeth F Sutton; Heinrich E Lob; Jiunn Song; YunWei Xia; Scott Butler; Chin-Chi Liu; Leanne M Redman; Jenny L Sones Journal: Am J Physiol Regul Integr Comp Physiol Date: 2017-01-25 Impact factor: 3.619
Authors: J J Miranda Geelhoed; Abigail Fraser; Kate Tilling; Li Benfield; George Davey Smith; Naveed Sattar; Scott M Nelson; Debbie A Lawlor Journal: Circulation Date: 2010-09-07 Impact factor: 29.690