Literature DB >> 19608562

Good syndrome accompanied by pure red cell aplasia.

Tetsuo Taniguchi1, Noriyasu Usami, Koji Kawaguchi, Kohei Yokoi.   

Abstract

Thymomas are often associated with various autoimmune disorders. We herein report a middle-aged female patient with thymoma and hypogammaglobulinemia (Good syndrome) who developed symptomatic normocytic anemia. Her computed tomography (CT) scans showed a cervico-mediastinal mass. The findings of a bone marrow biopsy suggested pure red cell aplasia (PRCA), and the serum levels of all immunoglobulins were extremely low. After the resection of the tumor, which was diagnosed to be Masaoka stage II and type AB thymoma, the normocytic anemia dramatically improved, but the hypogammaglobulinemia did not recover.

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Year:  2009        PMID: 19608562     DOI: 10.1510/icvts.2009.210393

Source DB:  PubMed          Journal:  Interact Cardiovasc Thorac Surg        ISSN: 1569-9285


  3 in total

1.  Thymectomy as an oncologic and immunologic treatment.

Authors:  Masatsugu Hamaji
Journal:  Transl Lung Cancer Res       Date:  2018-09

Review 2.  Case report and literature review on Good's syndrome, a form of acquired immunodeficiency associated with thymomas.

Authors:  Mark Henry Joven; Melvin P Palalay; Charlie Y Sonido
Journal:  Hawaii J Med Public Health       Date:  2013-02

3.  A case of synchronous triple autoimmune disorders secondary to thymoma: Pure red cell aplasia, Good's syndrome, and thymoma-associated multi-organ autoimmunity.

Authors:  Yuta Nakagawa; Kinnosuke Matsumoto; Makoto Yamamoto; Haruhiko Hirata; Takayuki Shiroyama; Kotaro Miyake; Yuji Yamamoto; Tomoki Kuge; Midori Yoneda; Yujiro Naito; Yasuhiko Suga; Kiyoharu Fukushima; Shohei Koyama; Kota Iwahori; Izumi Nagatomo; Yoshito Takeda; Atsushi Kumanogoh
Journal:  Respir Med Case Rep       Date:  2022-02-23
  3 in total

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