Literature DB >> 19606687

[Paliative procedures in cholangiocarcinomas--experience of 5 centers].

Jacek Smigielski1, Jarosław Hołyński, Maciej Kococik, Zbigniew Kococik, Mariusz Balcerczak, Janusz Sztompka, Jerzy Wojtysiak, Rafał Drozda, Renata Talar-Wojnarowska, Marek Pazurek, Ewa Małecka-Panas, Krzysztof Kołomecki, Marian Brocki.   

Abstract

UNLABELLED: Cholangiocarcinomas have been often met in daily practice. Biliar tract neoplasmas are the most important group in adenomas and papillomas. There is the medical and social problem with cancer patients because they call doctor too late when cancer changes reach a high level and only paliative procedures are recommended. In the most cases the prothesis implanted by ERCP and surgical digestive bypasses are applied. AIM OF THE STUDY: was to evaluate some therapeutic methods in paliative treatment applied in patients with biliary tract cancer.
MATERIAL AND METHODS: From 01.2003 to 12.2007 (5 years experience) in 4 departments of general surgery and departments of digestive tract diseases the medical treatment of 430 patients with biliary tract cancer was analyzed. All patients were divided into 3 groups: G1--prosthesis by ERCP; G2--percutaneously, transhepatic drainage of biliary tract; G3--surgical digestive bypass.
RESULTS: G1 techniques were applied in 75 patients, G2 in 14 cases and G3 in 74 cases. In the last group of patients the following procedures have been performed: triple bypass (TB) in 45 cases (62%), choledochoduodenostomy (ChD) in 7 cases (9%), gastroenterostomy (GE) in 10 patients (13%) and laparotomy with Kehr drainage in 12 patients (16%). The number of complications in G1 group was observed in 31%, in G2--42%, and in G3--63%. 30 days death rate was 14% in G1, 28% in G2 and 18% in G3. Over 12 months survival rate was in G1, 3 months in G2 and 15 months in G3. Differences are statistically sagnificant (p < 0.05).
CONCLUSIONS: From all applied methods of paliative treatment the best results were noticed in surgical digestive bypass and implantation of prosthesis by ERCP. After surgical treatment survival rate was higher, but the number of complications was higher in relation to another methods.

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Mesh:

Year:  2009        PMID: 19606687

Source DB:  PubMed          Journal:  Pol Merkur Lekarski        ISSN: 1426-9686


  4 in total

Review 1.  Malignant Biliary Obstruction: Evidence for Best Practice.

Authors:  Leonardo Zorrón Cheng Tao Pu; Rajvinder Singh; Cheong Kuan Loong; Eduardo Guimarães Hourneaux de Moura
Journal:  Gastroenterol Res Pract       Date:  2016-02-11       Impact factor: 2.260

2.  Percutaneous ultrasound-guided drainage of the biliary tree in palliative treatment of mechanical jaundice: 17 years of experience.

Authors:  Marcin Bednarek; Piotr Budzyński; Marek Poźniczek; Kazimierz Rembiasz
Journal:  Wideochir Inne Tech Maloinwazyjne       Date:  2012-05-31       Impact factor: 1.195

3.  Assessment of quality of life in patients with non-operated pancreatic cancer after videothoracoscopic splanchnicectomy.

Authors:  Jacek Smigielski; Lukasz Piskorz; Marcin Wawrzycki; Leszek Kutwin; Piotr Misiak; Marian Brocki
Journal:  Wideochir Inne Tech Maloinwazyjne       Date:  2011-09-30       Impact factor: 1.195

4.  Application of biochemical markers CA 19-9, CEA and C-reactive protein in diagnosis of malicious and benign pancreatic tumors.

Authors:  Jacek A Smigielski; Lukasz Piskorz; Marcin Wawrzycki; Przemysław Dobielski; Małgorzata Pikala; Sławomir Jabłoński; Marian Brocki
Journal:  Arch Med Sci       Date:  2013-08-08       Impact factor: 3.318

  4 in total

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