UNLABELLED: Multi-mapping sequence tags are a significant impediment to short-read sequencing platforms. These tags are routinely omitted from further analysis, leading to experimental bias and reduced coverage. Here, we present MuMRescueLite, a low-resource requirement version of the MuMRescue software that has been used by several next generation sequencing projects to probabilistically reincorporate multi-mapping tags into mapped short read data. AVAILABILITY AND IMPLEMENTATION: MuMRescueLite is written in Python; executables and documentation are available from http://genome.gsc.riken.jp/osc/english/software/.
UNLABELLED: Multi-mapping sequence tags are a significant impediment to short-read sequencing platforms. These tags are routinely omitted from further analysis, leading to experimental bias and reduced coverage. Here, we present MuMRescueLite, a low-resource requirement version of the MuMRescue software that has been used by several next generation sequencing projects to probabilistically reincorporate multi-mapping tags into mapped short read data. AVAILABILITY AND IMPLEMENTATION: MuMRescueLite is written in Python; executables and documentation are available from http://genome.gsc.riken.jp/osc/english/software/.
Authors: Eleonora de Klerk; Ivo F A C Fokkema; Klaske A M H Thiadens; Jelle J Goeman; Magnus Palmblad; Johan T den Dunnen; Marieke von Lindern; Peter A C 't Hoen Journal: Nucleic Acids Res Date: 2015-04-14 Impact factor: 16.971