| Literature DB >> 19604487 |
Abstract
Adenoviral vectors used in gene therapy induce inflammation, although the underlying mechanisms are currently unknown. In this issue of Immunity, Di Paolo et al. (2009) implicate interleukin-1 alpha (IL- 1 alpha) in virus-induced inflammation and identify the beta 3 integrin as the key receptor regulating IL-1 alpha activity.Entities:
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Year: 2009 PMID： 19604487 DOI： 10.1016/j.immuni.2009.07.001
Source DB: PubMed Journal: Immunity ISSN： 1074-7613 Impact factor: 31.745