Literature DB >> 19602631

Phosphatidic acid: a novel mechanical mechanism for how resistance exercise activates mTORC1 signalling.

Blake B Rasmussen1.   

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Year:  2009        PMID： 19602631      PMCID： PMC2742264          DOI： 10.1113/jphysiol.2009.176453

Source DB:  PubMed          Journal:  J Physiol        ISSN： 0022-3751            Impact factor:   5.182


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  11 in total

1.  Resistance exercise increases AMPK activity and reduces 4E-BP1 phosphorylation and protein synthesis in human skeletal muscle.

Authors:  Hans C Dreyer; Satoshi Fujita; Jerson G Cadenas; David L Chinkes; Elena Volpi; Blake B Rasmussen
Journal:  J Physiol       Date:  2006-07-27       Impact factor: 5.182

2.  Resistance exercise increases muscle protein synthesis and translation of eukaryotic initiation factor 2Bepsilon mRNA in a mammalian target of rapamycin-dependent manner.

Authors:  Neil Kubica; Douglas R Bolster; Peter A Farrell; Scot R Kimball; Leonard S Jefferson
Journal:  J Biol Chem       Date:  2004-12-10       Impact factor: 5.157

3.  Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo.

Authors:  S C Bodine; T N Stitt; M Gonzalez; W O Kline; G L Stover; R Bauerlein; E Zlotchenko; A Scrimgeour; J C Lawrence; D J Glass; G D Yancopoulos
Journal:  Nat Cell Biol       Date:  2001-11       Impact factor: 28.824

4.  Increased rates of muscle protein turnover and amino acid transport after resistance exercise in humans.

Authors:  G Biolo; S P Maggi; B D Williams; K D Tipton; R R Wolfe
Journal:  Am J Physiol       Date:  1995-03

5.  Mechanical stimuli and nutrients regulate rapamycin-sensitive signaling through distinct mechanisms in skeletal muscle.

Authors:  Troy A Hornberger; Shu Chien
Journal:  J Cell Biochem       Date:  2006-04-15       Impact factor: 4.429

6.  Rapamycin administration in humans blocks the contraction-induced increase in skeletal muscle protein synthesis.

Authors:  Micah J Drummond; Christopher S Fry; Erin L Glynn; Hans C Dreyer; Shaheen Dhanani; Kyle L Timmerman; Elena Volpi; Blake B Rasmussen
Journal:  J Physiol       Date:  2009-02-02       Impact factor: 5.182

7.  The role of phospholipase D and phosphatidic acid in the mechanical activation of mTOR signaling in skeletal muscle.

Authors:  T A Hornberger; W K Chu; Y W Mak; J W Hsiung; S A Huang; S Chien
Journal:  Proc Natl Acad Sci U S A       Date:  2006-03-14       Impact factor: 11.205

8.  Phosphorylation of p70(S6k) correlates with increased skeletal muscle mass following resistance exercise.

Authors:  K Baar; K Esser
Journal:  Am J Physiol       Date:  1999-01

9.  A functional insulin-like growth factor receptor is not necessary for load-induced skeletal muscle hypertrophy.

Authors:  Espen E Spangenburg; Derek Le Roith; Chris W Ward; Sue C Bodine
Journal:  J Physiol       Date:  2007-11-01       Impact factor: 5.182

10.  mVps34 is activated following high-resistance contractions.

Authors:  Matthew G MacKenzie; D Lee Hamilton; James T Murray; Peter M Taylor; Keith Baar
Journal:  J Physiol       Date:  2008-11-17       Impact factor: 5.182
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  1 in total

1.  Efficacy of phosphatidic acid ingestion on lean body mass, muscle thickness and strength gains in resistance-trained men.

Authors:  Jay R Hoffman; Jeffrey R Stout; David R Williams; Adam J Wells; Maren S Fragala; Gerald T Mangine; Adam M Gonzalez; Nadia S Emerson; William P McCormack; Tyler C Scanlon; Martin Purpura; Ralf Jäger
Journal:  J Int Soc Sports Nutr       Date:  2012-10-05       Impact factor: 5.150
  1 in total

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