Comparison of photoselective vaporization and standard transurethral resection of the prostate on urodynamics in patients with benign prostatic hyperplasia.

OBJECTIVES: To compare photoselective vaporization of the prostate (PVP) and transurethral resection of the prostate (TURP) in patients with benign prostatic hyperplasia.
METHODS: Patients were enrolled in a prospective non-randomized trial and underwent PVP (n = 78) and TURP (n = 51). Primary outcome variables included: International Prostate Symptom Score, quality-of-life score, urinary peak flow and post-void residual urine volume at 3, 6 and 12 months postoperatively. Secondary outcomes were urodynamic variables, including the index of bladder outlet obstruction (BOO) and detrusor contractility.
RESULTS: Improvement in all outcome variables after PVP was comparable to that after TURP within 12 months. Outcome based on urodynamic parameters was also similar. Pre/post median value of the BOO index was 63/2 in the PVP group and 61/5 in the TURP group. Pre/post rate of detrusor overactivity was 49%/27% in the PVP and 53%/29% in the TURP group. There was minimal change in detrusor contractility. Overall, morbidity was comparable in the two groups.
CONCLUSIONS: The 12-month outcome after PVP is similar to that of TURP with an effective relief from BOO and detrusor overactivity and minimal change in detrusor contractility.

RCT Entities:   Population Interventions Outcomes