Literature DB >> 19596566

FERM proteins in animal morphogenesis.

Ulrich Tepass1.   

Abstract

Proteins containing a FERM domain are ubiquitous components of the cytocortex of animal cells where they are engaged in structural, transport, and signaling functions. Recent years have seen a wealth of genetic studies in model organisms that explore FERM protein function in development and tissue organization. In addition, mutations in several FERM protein-encoding genes have been associated with human diseases. This review will provide a brief overview of the FERM domain structure and the FERM protein superfamily and then discuss recent advances in our understanding of the mechanism of function and developmental requirement of several FERM proteins including Moesin, Myosin-VIIA, Myosin-XV, Coracle/Band4.1 as well as Yurt and its vertebrate homologs Mosaic Eyes and EPB41L5/YMO1/Limulus.

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Year:  2009        PMID: 19596566     DOI: 10.1016/j.gde.2009.05.006

Source DB:  PubMed          Journal:  Curr Opin Genet Dev        ISSN: 0959-437X            Impact factor:   5.578


  41 in total

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4.  Time-varying causal inference from phosphoproteomic measurements in macrophage cells.

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Review 5.  Mechanisms of cell polarity and aquaporin sorting in the nephron.

Authors:  Bayram Edemir; Hermann Pavenstädt; Eberhard Schlatter; Thomas Weide
Journal:  Pflugers Arch       Date:  2011-02-16       Impact factor: 3.657

6.  Left-right patterning in the mouse requires Epb4.1l5-dependent morphogenesis of the node and midline.

Authors:  Jeffrey D Lee; Isabelle Migeotte; Kathryn V Anderson
Journal:  Dev Biol       Date:  2010-08-01       Impact factor: 3.582

7.  Talin autoinhibition is required for morphogenesis.

Authors:  Stephanie J Ellis; Benjamin T Goult; Michael J Fairchild; Nathan J Harris; Jenny Long; Paolo Lobo; Stefan Czerniecki; Filip Van Petegem; Frieder Schöck; Mark Peifer; Guy Tanentzapf
Journal:  Curr Biol       Date:  2013-09-05       Impact factor: 10.834

8.  A possible role for FRM-1, a C. elegans FERM family protein, in embryonic development.

Authors:  Boram Choi; Junsu Kang; Yang-Seo Park; Junho Lee; Nam Jeong Cho
Journal:  Mol Cells       Date:  2011-03-24       Impact factor: 5.034

9.  Linkage analyses in Caribbean Hispanic families identify novel loci associated with familial late-onset Alzheimer's disease.

Authors:  Sandra Barral; Rong Cheng; Christiane Reitz; Badri Vardarajan; Joseph Lee; Brian Kunkle; Gary Beecham; Laura S Cantwell; Margaret A Pericak-Vance; Lindsay A Farrer; Jonathan L Haines; Alison M Goate; Tatiana Foroud; Eric Boerwinkle; Gerard D Schellenberg; Richard Mayeux
Journal:  Alzheimers Dement       Date:  2015-10-01       Impact factor: 21.566

Review 10.  Organization and execution of the epithelial polarity programme.

Authors:  Enrique Rodriguez-Boulan; Ian G Macara
Journal:  Nat Rev Mol Cell Biol       Date:  2014-04       Impact factor: 94.444

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