| Literature DB >> 1959633 |
L L Sidorik1, O I Gudzera, V A Dragovoz, M A Tukalo, S F Beresten.
Abstract
Monospecific polyclonal antibodies (pAbs) against highly purified bovine seryl-tRNA synthetase (SerRS, EC 6.1.1.1) were prepared and their specificity tested. The interactions of pAbs with SerRS from different organisms were investigated by protein immunoblotting and ELISA methods. pAbs inhibit eukaryotic SerRS aminoacylating activity and exert no effect on SerRS activity from prokaryotes. It is proposed that prokaryotic and eukaryotic SerRS evolve from different ancestor genes.Entities:
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Year: 1991 PMID： 1959633 DOI： 10.1016/0014-5793(91)80838-t
Source DB: PubMed Journal: FEBS Lett ISSN： 0014-5793 Impact factor: 4.124