Altered distribution of plasma platelet-activating factor acetylhydrolase between high-density lipoprotein and low-density lipoprotein in patients with polycystic ovary syndrome.

To investigate the association of plasma platelet-activating factor (PAF) acetylhydrolase, high-density lipoprotein-associated PAF acetylhydrolase, and low-density lipoprotein-associated PAF acetylhydrolase activities with metabolic features in patients with polycystic ovary syndrome (PCOS) in Han Chinese women, 141 patients with PCOS and 140 healthy controls were recruited in this case-control study. The results of our study showed that the presence of the changed plasma PAF acetylhydrolase activity and distribution in women with PCOS could contribute to the low-grade chronic inflammation and increased risk of atherosclerosis in these patients.