Three new vanilloid derivatives from the stems of Baccaurea ramiflora.

Three new (1-3) and four known (4-7) compounds were isolated from the stems of Baccaurea ramiflora. By analysis of 1D, 2D NMR, and MS data, the new compounds were identified as 4'-O-(6- O-vanilloyl)-beta-D-glucopyranosyl tachioside D (1), 6'-O-vanilloylpicraquassioside D (2), and 6'-O-vanilloylicariside B(5) (3). Compound 1 exhibited significant DPPH radical-scavenging activity, with an IC(50) value of 36.9 microM, while compound 4 revealed weak antioxidant activity against H (2)O(2)-induced impairment in PC12 cells. Copyright Georg Thieme Verlag KG Stuttgart . New York.