Literature DB >> 19590996

Life-time adversities, reported thirteen years after a suicide attempt: relationship to recovery, 5HTTLPR genotype, and past and present morbidity.

Fredrik J Vang1, Mats Lindström, Charlotta Sunnqvist, Jessica Bah-Rösman, Aki Johanson, Lil Träskman-Bendz.   

Abstract

In this study, we investigated how adversities related to past and present morbidity, and genotype. Forty-two, suicide attempters and 22 matched control patients were followed-up after 13 years. Life-time adversities were explored in an interview, and the patients were reassessed psychiatrically. The serotonin-transporter-linked promotor region (5-HTTLPR) was typed. More adversities were reported by suicide attempters than controls, and by still-ill than recovered suicide attempters. Adversities reported at follow-up were related to psychiatric morbidity at follow-up, but not to morbidity 13 years earlier. The 5-HTTLPR, genotype was associated with reported adversities, but not chances of recovery. Adversities potentially affected chronic morbidity. 5-HTTLPR genotype did not affect long-term recovery.

Entities:  

Mesh:

Substances:

Year:  2009        PMID: 19590996     DOI: 10.1080/13811110903044328

Source DB:  PubMed          Journal:  Arch Suicide Res        ISSN: 1381-1118


  1 in total

1.  Association of the 5HTR2A gene with suicidal behavior: case-control study and updated meta-analysis.

Authors:  Thelma Beatriz González-Castro; Carlos Tovilla-Zárate; Isela Juárez-Rojop; Sherezada Pool García; Martha Patricia Velázquez-Sánchez; Alma Genis; Humberto Nicolini; Lilia López Narváez
Journal:  BMC Psychiatry       Date:  2013-01-12       Impact factor: 3.630

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.