Z Biró1, Z Balla. 1. Department of Ophthalmology, University of Pécs, Medical School Pécs, Pécs, Hungary. zsolt.biro@aok.pte.hu
Abstract
PURPOSE: The first aim (I.) was to measure the change of macular thickness in diabetic (DM group) and nondiabetic patients (NORMAL group), the values of operated eye (OP) were compared I.A.) to the fellow, non-operated eye (CONTROL) and I.B.) to preoperative baseline value of the operated eye (PRE). The second aim (II.) was to compare postoperative macular thickening of DM group to NORMAL group eyes. METHODS: Retinal thickness values of the foveal and perifoveal (fovea+3.0 mm, fovea+6.0 mm) sectors and the minimum values were measured in a prospective study using optical coherence tomography (OCT) in 18 eyes of 18 diabetic patients and 53 eyes of 53 nondiabetic patients who underwent uneventful cataract surgery. Data were collected on the preoperative day and on postoperative 1, 7, 30, and 60 days. Student's t-test was used for statistical analysis. RESULTS: No significant change of the thickness values could be measured one day after surgery. However, a significant increase could be detected on the postoperative 7, 30, and 60 days in the perifoveal 3.0 mm and 6.0 mm sectors either calculated alone or averaged together with the foveal values. The initial (preoperative) average value of 232.7+/-3.5 microm (mean+/-SEM, n=144) in the 6.0 mm perifoveal region increased to 246.0+/-8.2 microm (mean+/-SEM, n=120, P=0.032) one week, to 249.9+/-5.1 microm (n=112, P=0.017) one month, and to 249.5+/-6.2 microm (n=104, P=0.009) 2 months after surgery. DISCUSSION: Our results indicate that diabetes did not influence significantly the thickening of the macular regions after uncomplicated cataract surgery.
PURPOSE: The first aim (I.) was to measure the change of macular thickness in diabetic (DM group) and nondiabeticpatients (NORMAL group), the values of operated eye (OP) were compared I.A.) to the fellow, non-operated eye (CONTROL) and I.B.) to preoperative baseline value of the operated eye (PRE). The second aim (II.) was to compare postoperative macular thickening of DM group to NORMAL group eyes. METHODS: Retinal thickness values of the foveal and perifoveal (fovea+3.0 mm, fovea+6.0 mm) sectors and the minimum values were measured in a prospective study using optical coherence tomography (OCT) in 18 eyes of 18 diabeticpatients and 53 eyes of 53 nondiabeticpatients who underwent uneventful cataract surgery. Data were collected on the preoperative day and on postoperative 1, 7, 30, and 60 days. Student's t-test was used for statistical analysis. RESULTS: No significant change of the thickness values could be measured one day after surgery. However, a significant increase could be detected on the postoperative 7, 30, and 60 days in the perifoveal 3.0 mm and 6.0 mm sectors either calculated alone or averaged together with the foveal values. The initial (preoperative) average value of 232.7+/-3.5 microm (mean+/-SEM, n=144) in the 6.0 mm perifoveal region increased to 246.0+/-8.2 microm (mean+/-SEM, n=120, P=0.032) one week, to 249.9+/-5.1 microm (n=112, P=0.017) one month, and to 249.5+/-6.2 microm (n=104, P=0.009) 2 months after surgery. DISCUSSION: Our results indicate that diabetes did not influence significantly the thickening of the macular regions after uncomplicated cataract surgery.